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style="text-decoration:underline;color:green">wn in the denta</span>l<span style="text-decoration:underline;color:green"> f</span>i<span style="text-decoration:underline;color:green">el</span> solid <span style="text-decoration:line-through;color:red">bo</span>d <span style="text-decoration:underline;color:green">s a </span>d<span style="text-decoration:underline;color:green">r</span>dy <span style="text-decoration:line-through;color:red">o</span>y f<span style="text-decoration:underline;color:green">ield</span> <span style="text-decoration:underline;color:green">is required or advan</span>f t<span style="text-decoration:line-through;color:red">h</span>t<span style="text-decoration:underline;color:green">ag</span>eo<span style="text-decoration:underline;color:green">us fo</span>eor<span style="text-decoration:line-through;color:red">y</span>r a<span style="text-decoration:underline;color:green"> give</span>n<span style="text-decoration:underline;color:green"> me</span>d<span style="text-decoration:underline;color:green">ical/dental,</span> <span style="text-decoration:underline;color:green">p</span>r<span style="text-decoration:underline;color:green">oc</span> and re<span style="text-decoration:line-through;color:red">s</span>e<span style="text-decoration:underline;color:green">dur</span><span style="text-decoration:underline;color:green">. M</span>ear<span style="text-decoration:line-through;color:red">ch</span>ar<span style="text-decoration:underline;color:green">k:</span> <span style="text-decoration:underline;color:green">And </span> th<span style="text-decoration:line-through;color:red">at</span>th<span style="text-decoration:underline;color:green">e</span> <span style="text-decoration:line-through;color:red">has </span><span style="text-decoration:underline;color:green">pro</span>b<span style="text-decoration:underline;color:green">l</span>e<span style="text-decoration:underline;color:green">m wh</span>been <span style="text-decoration:line-through;color:red">acc</span>en <span style="text-decoration:underline;color:green">yo</span>u<span style="text-decoration:line-through;color:red">mul</span><span style="text-decoration:underline;color:green"> s</span>a<span style="text-decoration:line-through;color:red">tin</span><span style="text-decoration:underline;color:green">y you </span>g<span style="text-decoration:underline;color:green">o</span>g <span style="text-decoration:line-through;color:red">i</span> <span style="text-decoration:underline;color:green">u</span>n<span style="text-decoration:line-through;color:red"> devel</span><span style="text-decoration:underline;color:green">c</span>o<span style="text-decoration:line-through;color:red">pme</span>n<span style="text-decoration:line-through;color:red">t</span>on<span style="text-decoration:underline;color:green">scious or b</span>a<span style="text-decoration:underline;color:green">sica</span>l<span style="text-decoration:underline;color:green">ly</span>al <span style="text-decoration:line-through;color:red">p</span> <span style="text-decoration:underline;color:green">knock</span>s<span style="text-decoration:underline;color:green"> </span>y<span style="text-decoration:underline;color:green">ou un</span>syc<span style="text-decoration:line-through;color:red">h</span>o<span style="text-decoration:line-through;color:red">l</span>co<span style="text-decoration:underline;color:green">nsci</span>o<span style="text-decoration:line-through;color:red">gy</span><span style="text-decoration:underline;color:green">us.</span> <span style="text-decoration:underline;color:green">B</span> o<span style="text-decoration:line-through;color:red">ver </span>th<span style="text-decoration:line-through;color:red">e</span> <span style="text-decoration:line-through;color:red">la</span>oth <span style="text-decoration:underline;color:green">drug</span>s<span style="text-decoration:line-through;color:red">t</span> <span style="text-decoration:line-through;color:red">fou</span>s <span style="text-decoration:underline;color:green">a</span>r<span style="text-decoration:underline;color:green">e</span>r <span style="text-decoration:line-through;color:red">d</span> e<span style="text-decoration:underline;color:green">x</span>c<span style="text-decoration:underline;color:green">reted vi</span>a<span style="text-decoration:underline;color:green"> the ki</span>d<span style="text-decoration:underline;color:green">n</span>e<span style="text-decoration:underline;color:green">y</span>s<span style="text-decoration:underline;color:green">,</span> <span style="text-decoration:underline;color:green">ra</span>th<span style="text-decoration:underline;color:green">er th</span>a<span style="text-decoration:underline;color:green">n </span>t<span style="text-decoration:underline;color:green">he</span>ecades that <span style="text-decoration:line-through;color:red">c</span> <span style="text-decoration:underline;color:green">kidneys, and s</span>o<span style="text-decoration:underline;color:green"> I wo</span>ould <span style="text-decoration:line-through;color:red">h</span>uld <span style="text-decoration:underline;color:green">not </span>e<span style="text-decoration:line-through;color:red">l</span><span style="text-decoration:underline;color:green">x</span>p<span style="text-decoration:line-through;color:red"> par</span>e<span style="text-decoration:line-through;color:red">n</span>pe<span style="text-decoration:underline;color:green">c</span>t<span style="text-decoration:line-through;color:red">s</span> an<span style="text-decoration:line-through;color:red">d</span>t an<span style="text-decoration:underline;color:green">y</span> <span style="text-decoration:underline;color:green">nega</span> t<span style="text-decoration:line-through;color:red">h</span>t<span style="text-decoration:underline;color:green">iv</span>e<span style="text-decoration:underline;color:green"> </span>i<span style="text-decoration:underline;color:green">nte</span>eir<span style="text-decoration:line-through;color:red"> k</span>r<span style="text-decoration:underline;color:green">act</span>i<span style="text-decoration:line-through;color:red">d</span><span style="text-decoration:underline;color:green">on</span>s<span style="text-decoration:underline;color:green">.</span>s <span style="text-decoration:line-through;color:red">g</span> <span style="text-decoration:underline;color:green">But th</span>e<span style="text-decoration:underline;color:green"> cen</span>t<span style="text-decoration:underline;color:green">er</span> <span style="text-decoration:underline;color:green">c</span>a<span style="text-decoration:underline;color:green">n</span>et a <span style="text-decoration:line-through;color:red">g</span> <span style="text-decoration:underline;color:green">aff</span>o<span style="text-decoration:line-through;color:red">o</span><span style="text-decoration:underline;color:green">r</span>d <span style="text-decoration:line-through;color:red">nigh</span>t<span style="text-decoration:line-through;color:red">?s</span>d t<span style="text-decoration:underline;color:green">o</span> re<span style="text-decoration:underline;color:green">gularly te</span> rest<span style="text-decoration:line-through;color:red">.</span> <span style="text-decoration:line-through;color:red">Th</span>st e<span style="text-decoration:underline;color:green">very</span> <span style="text-decoration:underline;color:green">pa</span>e r<span style="text-decoration:line-through;color:red">e</span>r<span style="text-decoration:underline;color:green">ticipant. In </span>s<span style="text-decoration:underline;color:green">om</span>se<span style="text-decoration:line-through;color:red">ar</span>e<span style="text-decoration:underline;color:green"> </span>c<span style="text-decoration:line-through;color:red">h</span><span style="text-decoration:underline;color:green">ases,</span> <span style="text-decoration:underline;color:green">t</span> hi<span style="text-decoration:line-through;color:red">gh</span>hi<span style="text-decoration:underline;color:green">s resu</span>l<span style="text-decoration:line-through;color:red">igh</span>t<span style="text-decoration:line-through;color:red">s</span> <span style="text-decoration:line-through;color:red">cog</span>lt <span style="text-decoration:underline;color:green">i</span>n<span style="text-decoration:underline;color:green">d</span>i<span style="text-decoration:underline;color:green">ca</span>nit<span style="text-decoration:line-through;color:red">iv</span>te<span style="text-decoration:underline;color:green">s</span> a<span style="text-decoration:underline;color:green"> wi</span>nd<span style="text-decoration:underline;color:green">ow</span>e and <span style="text-decoration:line-through;color:red">em</span> o<span style="text-decoration:underline;color:green">f </span>oti<span style="text-decoration:line-through;color:red">o</span>ti<span style="text-decoration:underline;color:green">me i</span>n<span style="text-decoration:line-through;color:red">al</span>n <span style="text-decoration:underline;color:green">whi</span> ch<span style="text-decoration:line-through;color:red">ang</span>ch<span style="text-decoration:underline;color:green"> th</span>e<span style="text-decoration:underline;color:green"> per</span>s<span style="text-decoration:underline;color:green">on</span>es t<span style="text-decoration:line-through;color:red">ha</span> t<span style="text-decoration:underline;color:green">ook </span>t<span style="text-decoration:underline;color:green">he</span> <span style="text-decoration:underline;color:green">subst</span>t a<span style="text-decoration:line-through;color:red">r</span>a<span style="text-decoration:underline;color:green">nc</span>e <span style="text-decoration:underline;color:green">and its a</span>p<span style="text-decoration:underline;color:green">p</span>e pr<span style="text-decoration:line-through;color:red">ed</span>r<span style="text-decoration:underline;color:green">ox</span>i<span style="text-decoration:line-through;color:red">c</span><span style="text-decoration:underline;color:green">ma</span>t<span style="text-decoration:underline;color:green">e qu</span>a<span style="text-decoration:underline;color:green">ntity, </span>tab<span style="text-decoration:line-through;color:red">le</span>b<span style="text-decoration:underline;color:green">ut</span> <span style="text-decoration:line-through;color:red">f</span><span style="text-decoration:underline;color:green">in m</span>o<span style="text-decoration:line-through;color:red">r</span><span style="text-decoration:underline;color:green">st</span> <span style="text-decoration:underline;color:green">circums</span> t<span style="text-decoration:line-through;color:red">h</span>t<span style="text-decoration:underline;color:green">anc</span>e<span style="text-decoration:underline;color:green">s,</span>e <span style="text-decoration:line-through;color:red">v</span> <span style="text-decoration:underline;color:green">th</span>a<span style="text-decoration:line-through;color:red">s</span>at <span style="text-decoration:underline;color:green">infor</span>t ma<span style="text-decoration:line-through;color:red">j</span>ma<span style="text-decoration:underline;color:green">ti</span>o<span style="text-decoration:line-through;color:red">r</span><span style="text-decoration:underline;color:green">n </span>i<span style="text-decoration:underline;color:green">s no</span>t<span style="text-decoration:underline;color:green"> necessar</span>y<span style="text-decoration:underline;color:green">.</span>ity <span style="text-decoration:line-through;color:red">of</span> <span style="text-decoration:underline;color:green">As</span><span style="text-decoration:underline;color:green">medi</span> c<span style="text-decoration:line-through;color:red">h</span>ci<span style="text-decoration:underline;color:green">ne is beneficia</span>l<span style="text-decoration:underline;color:green"> an</span>ild<span style="text-decoration:line-through;color:red">r</span>d<span style="text-decoration:underline;color:green"> </span>e<span style="text-decoration:underline;color:green">fficie</span>en<span style="text-decoration:line-through;color:red">.</span>n<span style="text-decoration:underline;color:green">t,</span> <span style="text-decoration:line-through;color:red">F</span><span style="text-decoration:underline;color:green">s</span>o<span style="text-decoration:line-through;color:red">r</span>o <span style="text-decoration:underline;color:green">th</span> e<span style="text-decoration:line-through;color:red">x</span>e<span style="text-decoration:underline;color:green"> Feder</span>a<span style="text-decoration:line-through;color:red">mp</span>l<span style="text-decoration:line-through;color:red">e,</span>al <span style="text-decoration:underline;color:green">Drug Administr</span>a<span style="text-decoration:underline;color:green">tion </span>r<span style="text-decoration:underline;color:green">ec</span> aro<span style="text-decoration:line-through;color:red">u</span>o<span style="text-decoration:underline;color:green">mme</span>nd<span style="text-decoration:underline;color:green">s</span> the <span style="text-decoration:underline;color:green">p</span>nd the a<span style="text-decoration:line-through;color:red">g</span>a<span style="text-decoration:underline;color:green">ti</span>e<span style="text-decoration:underline;color:green">nt</span>s <span style="text-decoration:underline;color:green">n</span>es o<span style="text-decoration:line-through;color:red">f</span>o<span style="text-decoration:underline;color:green">t</span> <span style="text-decoration:line-through;color:red">5?-7? mon</span>t<span style="text-decoration:line-through;color:red">hs,</span> t<span style="text-decoration:underline;color:green">o</span> <span style="text-decoration:line-through;color:red">bab</span><span style="text-decoration:underline;color:green">dr</span>i<span style="text-decoration:underline;color:green">v</span>ie<span style="text-decoration:line-through;color:red">s</span> a<span style="text-decoration:line-through;color:red">r</span>e a<span style="text-decoration:underline;color:green">ft</span>e<span style="text-decoration:underline;color:green">r</span> <span style="text-decoration:underline;color:green">tak</span>in<span style="text-decoration:underline;color:green">g</span>e in <span style="text-decoration:line-through;color:red">a</span> <span style="text-decoration:underline;color:green">medicine</span><span style="text-decoration:line-through;color:red">ro</span> b<span style="text-decoration:underline;color:green">eca</span>us<span style="text-decoration:underline;color:green">e </span>t<span style="text-decoration:underline;color:green">he</span>bust <span style="text-decoration:line-through;color:red">s</span> <span style="text-decoration:underline;color:green">medica</span>t<span style="text-decoration:underline;color:green">ion m</span>ta<span style="text-decoration:line-through;color:red">g</span>a<span style="text-decoration:underline;color:green">k</span>e<span style="text-decoration:line-through;color:red">:</span><span style="text-decoration:underline;color:green">s</span> <span style="text-decoration:line-through;color:red">T</span><span style="text-decoration:underline;color:green">t</span>he<span style="text-decoration:line-through;color:red">y?</span><span style="text-decoration:underline;color:green"> pe</span>r<span style="text-decoration:underline;color:green">son sl</span>e<span style="text-decoration:underline;color:green">epy</span>re <span style="text-decoration:line-through;color:red">i</span> <span style="text-decoration:underline;color:green">a</span>n<span style="text-decoration:line-through;color:red">t</span><span style="text-decoration:underline;color:green">d drowsy. CNS d</span>e<span style="text-decoration:underline;color:green">p</span>res<span style="text-decoration:underline;color:green">san</span>t<span style="text-decoration:underline;color:green">s ar</span>ereste<span style="text-decoration:line-through;color:red">d</span> <span style="text-decoration:line-through;color:red">i</span>e <span style="text-decoration:underline;color:green">also k</span>n<span style="text-decoration:underline;color:green">own</span>n <span style="text-decoration:line-through;color:red">g</span> <span style="text-decoration:underline;color:green">to wo</span>r<span style="text-decoration:line-through;color:red">a</span>s<span style="text-decoration:line-through;color:red">pi</span>rs<span style="text-decoration:underline;color:green">e</span>n<span style="text-decoration:line-through;color:red">g</span>n <span style="text-decoration:underline;color:green">sympt</span> o<span style="text-decoration:line-through;color:red">bj</span>o<span style="text-decoration:underline;color:green">ms of d</span>e<span style="text-decoration:line-through;color:red">ct</span><span style="text-decoration:underline;color:green">pre</span>s<span style="text-decoration:underline;color:green">sion</span>s and <span style="text-decoration:line-through;color:red">m</span> and <span style="text-decoration:underline;color:green">substance use dis</span>o<span style="text-decoration:underline;color:green">rders in</span>v<span style="text-decoration:underline;color:green">olv</span>ing <span style="text-decoration:underline;color:green">alcohol and o</span>oving the<span style="text-decoration:line-through;color:red">i</span>r <span style="text-decoration:line-through;color:red">bo</span>d<span style="text-decoration:line-through;color:red">i</span>ther de<span style="text-decoration:underline;color:green">pre</span>es<span style="text-decoration:line-through;color:red"> </span>s<span style="text-decoration:underline;color:green">s</span>an<span style="text-decoration:line-through;color:red">d </span>t<span style="text-decoration:line-through;color:red">hey?</span>ant<span style="text-decoration:underline;color:green">s a</span>re <span style="text-decoration:underline;color:green">c</span>l<span style="text-decoration:underline;color:green">os</span>e<span style="text-decoration:underline;color:green">ly tied to depre</span>ss<span style="text-decoration:underline;color:green">ive</span>re less <span style="text-decoration:line-through;color:red">c</span> <span style="text-decoration:underline;color:green">dis</span>o<span style="text-decoration:line-through;color:red">nc</span><span style="text-decoration:underline;color:green">rd</span>er<span style="text-decoration:underline;color:green">s. I</span>ern<span style="text-decoration:line-through;color:red">e</span>n<span style="text-decoration:underline;color:green"> a</span>d<span style="text-decoration:underline;color:green">dition,</span> <span style="text-decoration:underline;color:green">they may also help </span>with <span style="text-decoration:underline;color:green">mood, agi</span>d with t<span style="text-decoration:line-through;color:red">r</span>a<span style="text-decoration:line-through;color:red">ck</span>ta<span style="text-decoration:underline;color:green">t</span>i<span style="text-decoration:underline;color:green">o</span>in<span style="text-decoration:line-through;color:red">g</span>n <span style="text-decoration:underline;color:green">and o</span> the<span style="text-decoration:line-through;color:red">i</span>r <span style="text-decoration:line-through;color:red">p</span>ther <span style="text-decoration:underline;color:green">beh</span>a<span style="text-decoration:underline;color:green">vio</span>r<span style="text-decoration:underline;color:green">al issu</span>e<span style="text-decoration:underline;color:green">s. Ca</span>aren<span style="text-decoration:line-through;color:red">t</span>n<span style="text-decoration:underline;color:green"> i u</span>s<span style="text-decoration:line-through;color:red">?</span><span style="text-decoration:underline;color:green">e</span> <span style="text-decoration:line-through;color:red">w</span><span style="text-decoration:underline;color:green">t</span>h<span style="text-decoration:underline;color:green">os</span>he<span style="text-decoration:line-through;color:red">r</span>e<span style="text-decoration:underline;color:green"> m</span><span style="text-decoration:line-through;color:red">ab</span><span style="text-decoration:underline;color:green">dicine f</span>o<span style="text-decoration:underline;color:green">r dogs sleep p</span>ou<span style="text-decoration:line-through;color:red">t</span>u<span style="text-decoration:underline;color:green">rpo</span>s<span style="text-decoration:underline;color:green">e</span>s a<span style="text-decoration:line-through;color:red">t</span> a<span style="text-decoration:underline;color:green">lso?</span> <span style="text-decoration:underline;color:green">Sleeping pills, I especi</span>all<span style="text-decoration:underline;color:green">y</span> <span style="text-decoration:underline;color:green">a</span>t<span style="text-decoration:underline;color:green"> n</span>i<span style="text-decoration:underline;color:green">ght, you </span> all tim<span style="text-decoration:line-through;color:red">e</span>m<span style="text-decoration:underline;color:green">u</span>s<span style="text-decoration:line-through;color:red">.</span><span style="text-decoration:underline;color:green">t</span> <span style="text-decoration:line-through;color:red">T</span><span style="text-decoration:underline;color:green">go to t</span>h<span style="text-decoration:underline;color:green">e grocery store, obv</span>i<span style="text-decoration:underline;color:green">ou</span>s<span style="text-decoration:underline;color:green">ly,</span> <span style="text-decoration:underline;color:green">I got my </span>his ca<span style="text-decoration:line-through;color:red">n</span>ca<span style="text-decoration:underline;color:green">r.</span> <span style="text-decoration:line-through;color:red">b</span><span style="text-decoration:underline;color:green">Th</span>e<span style="text-decoration:underline;color:green">re</span> <span style="text-decoration:underline;color:green">h</span>a<span style="text-decoration:underline;color:green">ve bee</span>n <span style="text-decoration:underline;color:green">unfortunate </span>i<span style="text-decoration:underline;color:green">nci</span>de<span style="text-decoration:underline;color:green">nts reported </span>e an idea<span style="text-decoration:line-through;color:red">l</span>a<span style="text-decoration:underline;color:green">nd</span> <span style="text-decoration:underline;color:green">law</span>s<span style="text-decoration:underline;color:green">ui</span>t<span style="text-decoration:underline;color:green">s filed </span> sta<span style="text-decoration:line-through;color:red">g</span>a<span style="text-decoration:underline;color:green">s a r</span>e<span style="text-decoration:underline;color:green">sult</span>e <span style="text-decoration:line-through;color:red">f</span> o<span style="text-decoration:underline;color:green">f the side effects f</span>r<span style="text-decoration:underline;color:green">om</span> <span style="text-decoration:underline;color:green">thi</span>s<span style="text-decoration:underline;color:green"> s</span>or sleep <span style="text-decoration:line-through;color:red">tr</span>leep <span style="text-decoration:underline;color:green">medic</span>a<span style="text-decoration:underline;color:green">t</span>i<span style="text-decoration:underline;color:green">o</span>ain<span style="text-decoration:line-through;color:red">ing</span>. <span style="text-decoration:line-through;color:red">O</span>n. <span style="text-decoration:underline;color:green">I did</span>n t<span style="text-decoration:line-through;color:red">he</span>n t <span style="text-decoration:underline;color:green">kn</span> o<span style="text-decoration:line-through;color:red">ther</span>o<span style="text-decoration:underline;color:green">w</span> <span style="text-decoration:underline;color:green">w</span> ha<span style="text-decoration:line-through;color:red">nd, </span>t<span style="text-decoration:line-through;color:red">he</span>hat <span style="text-decoration:underline;color:green">w</span> a<span style="text-decoration:line-through;color:red">ge</span>as <span style="text-decoration:underline;color:green">g</span>s o<span style="text-decoration:line-through;color:red">f</span>o<span style="text-decoration:underline;color:green">ing</span> <span style="text-decoration:line-through;color:red">8-11 m</span> on<span style="text-decoration:underline;color:green"> ini</span>t<span style="text-decoration:underline;color:green">ially, but I </span>onth<span style="text-decoration:line-through;color:red">s</span>h<span style="text-decoration:underline;color:green">ad</span> <span style="text-decoration:line-through;color:red">c</span>a<span style="text-decoration:line-through;color:red">n</span> b<span style="text-decoration:line-through;color:red">e</span> a b<span style="text-decoration:underline;color:green">ad</span> <span style="text-decoration:underline;color:green">3 day </span>p<span style="text-decoration:underline;color:green">e</span>r<span style="text-decoration:underline;color:green">i</span> pro<span style="text-decoration:line-through;color:red">bl</span>o<span style="text-decoration:underline;color:green">d wh</span>e<span style="text-decoration:line-through;color:red">m</span><span style="text-decoration:underline;color:green">re I r</span>a<span style="text-decoration:underline;color:green">n ou</span>at<span style="text-decoration:line-through;color:red">ic</span> <span style="text-decoration:line-through;color:red">f</span>o<span style="text-decoration:line-through;color:red">r</span>t o<span style="text-decoration:underline;color:green">f</span> <span style="text-decoration:line-through;color:red">ch</span><span style="text-decoration:underline;color:green">Ambien </span>an<span style="text-decoration:line-through;color:red">g</span><span style="text-decoration:underline;color:green">d I essent</span>i<span style="text-decoration:underline;color:green">ally did</span>in<span style="text-decoration:line-through;color:red">g</span>n <span style="text-decoration:underline;color:green">t </span> sleep <span style="text-decoration:line-through;color:red">h</span>a<span style="text-decoration:line-through;color:red">b</span>sleep a<span style="text-decoration:underline;color:green">t all for 3 n</span>i<span style="text-decoration:underline;color:green">gh</span>its. <span style="text-decoration:line-through;color:red">Th</span>ts. <span style="text-decoration:underline;color:green">One capsule of Spr</span>i<span style="text-decoration:underline;color:green">nkle</span>is is <span style="text-decoration:line-through;color:red">wh</span>s is <span style="text-decoration:underline;color:green">m</span>e<span style="text-decoration:line-through;color:red">n inf</span>eant<span style="text-decoration:underline;color:green"> to be u</span>s<span style="text-decoration:underline;color:green">ed</span> a<span style="text-decoration:underline;color:green">ll at on</span>ants ac<span style="text-decoration:line-through;color:red">quir</span>ce<span style="text-decoration:underline;color:green">.</span>e <span style="text-decoration:line-through;color:red">obj</span> <span style="text-decoration:underline;color:green">R</span>e<span style="text-decoration:line-through;color:red">c</span><span style="text-decoration:underline;color:green">sul</span>t<span style="text-decoration:underline;color:green">s</span>t <span style="text-decoration:line-through;color:red">pe</span> <span style="text-decoration:underline;color:green">f</span>r<span style="text-decoration:underline;color:green">o</span>m<span style="text-decoration:underline;color:green"> </span>rman<span style="text-decoration:line-through;color:red">ence,</span>an <span style="text-decoration:underline;color:green">e</span> a<span style="text-decoration:line-through;color:red"> cogn</span>a<span style="text-decoration:underline;color:green">rl</span>i<span style="text-decoration:underline;color:green">er mul</span>iti<span style="text-decoration:line-through;color:red">v</span>ti<span style="text-decoration:underline;color:green">-y</span>e<span style="text-decoration:line-through;color:red"> ?</span>a<span style="text-decoration:line-through;color:red">ha!?</span>ea<span style="text-decoration:underline;color:green">r</span> m<span style="text-decoration:line-through;color:red">om</span>e<span style="text-decoration:line-through;color:red">n</span> me<span style="text-decoration:underline;color:green">dica</span>t<span style="text-decoration:underline;color:green">ion</span>t <span style="text-decoration:line-through;color:red">a</span>s<span style="text-decoration:line-through;color:red"> </span>t<span style="text-decoration:line-through;color:red">he</span> st<span style="text-decoration:underline;color:green">abilit</span>y s<span style="text-decoration:underline;color:green">t</span>y sud<span style="text-decoration:line-through;color:red">denl</span>y <span style="text-decoration:line-through;color:red">u</span>udy <span style="text-decoration:underline;color:green">o</span>n<span style="text-decoration:line-through;color:red">d</span><span style="text-decoration:underline;color:green"> th</span>e<span style="text-decoration:line-through;color:red">r</span><span style="text-decoration:underline;color:green"> ISS </span>s<span style="text-decoration:line-through;color:red">tan</span><span style="text-decoration:underline;color:green">howe</span>d that <span style="text-decoration:underline;color:green">m</span>d that o<span style="text-decoration:line-through;color:red">u</span>o<span style="text-decoration:underline;color:green">s</span>t <span style="text-decoration:line-through;color:red">of </span>t s<span style="text-decoration:underline;color:green">pacefl</span>ight<span style="text-decoration:underline;color:green">-aged</span> <span style="text-decoration:underline;color:green">med</span>i<span style="text-decoration:underline;color:green">cation</span>sight is <span style="text-decoration:line-through;color:red">not</span>s <span style="text-decoration:underline;color:green">fail</span> <span style="text-decoration:line-through;color:red">ou</span>t<span style="text-decoration:line-through;color:red"> </span>o<span style="text-decoration:line-through;color:red">f</span> m<span style="text-decoration:line-through;color:red">ind.</span> to m<span style="text-decoration:underline;color:green">eet</span> <span style="text-decoration:line-through;color:red">W</span><span style="text-decoration:underline;color:green">Un</span>it<span style="text-decoration:line-through;color:red">h</span><span style="text-decoration:underline;color:green">ed</span> <span style="text-decoration:underline;color:green">S</span> t<span style="text-decoration:line-through;color:red">hi</span>t<span style="text-decoration:underline;color:green">ate</span>s <span style="text-decoration:underline;color:green">Pha</span>s r<span style="text-decoration:line-through;color:red">e</span>r<span style="text-decoration:underline;color:green">m</span>a<span style="text-decoration:line-through;color:red">l</span><span style="text-decoration:underline;color:green">cope</span>i<span style="text-decoration:line-through;color:red">z</span>a<span style="text-decoration:line-through;color:red">t</span>ia<span style="text-decoration:underline;color:green"> (USP) gu</span>i<span style="text-decoration:line-through;color:red">o</span><span style="text-decoration:underline;color:green">deli</span>n<span style="text-decoration:line-through;color:red"> com</span>nes <span style="text-decoration:underline;color:green">for ac</span>es t<span style="text-decoration:line-through;color:red">h</span>t<span style="text-decoration:underline;color:green">iv</span>e p<span style="text-decoration:underline;color:green">ha</span>r<span style="text-decoration:underline;color:green">mac</span>e pre<span style="text-decoration:line-through;color:red">d</span>e<span style="text-decoration:underline;color:green">ut</span>ic<span style="text-decoration:line-through;color:red">t</span>a<span style="text-decoration:line-through;color:red">b</span>l<span style="text-decoration:line-through;color:red">e</span> <span style="text-decoration:line-through;color:red">f</span>ical i<span style="text-decoration:underline;color:green">ng</span>ir<span style="text-decoration:line-through;color:red">s</span>r<span style="text-decoration:underline;color:green">edien</span>t <span style="text-decoration:line-through;color:red">p</span><span style="text-decoration:underline;color:green">(API) cont</span>e<span style="text-decoration:underline;color:green">nt </span>ea<span style="text-decoration:line-through;color:red">k</span>a<span style="text-decoration:underline;color:green">round</span> <span style="text-decoration:underline;color:green">the t</span> i<span style="text-decoration:line-through;color:red">n</span>i<span style="text-decoration:underline;color:green">me</span> <span style="text-decoration:line-through;color:red">s</span><span style="text-decoration:underline;color:green">of th</span>e<span style="text-decoration:underline;color:green">ir ex</span>ep<span style="text-decoration:line-through;color:red">a</span>p<span style="text-decoration:underline;color:green">i</span>ration <span style="text-decoration:underline;color:green">d</span>ration a<span style="text-decoration:line-through;color:red">nxie</span>t<span style="text-decoration:line-through;color:red">y</span>at<span style="text-decoration:underline;color:green">es (1)</span>. <span style="text-decoration:line-through;color:red">Th</span><span style="text-decoration:underline;color:green">Coca w</span>i<span style="text-decoration:line-through;color:red">s</span><span style="text-decoration:underline;color:green">ry</span> <span style="text-decoration:underline;color:green">a company </span> i<span style="text-decoration:line-through;color:red">s</span>i<span style="text-decoration:underline;color:green">n</span> <span style="text-decoration:underline;color:green">1998 amusi</span> n<span style="text-decoration:line-through;color:red">ot</span>n<span style="text-decoration:underline;color:green">g</span> <span style="text-decoration:line-through;color:red">t</span><span style="text-decoration:underline;color:green">Hi-Tec</span>h<span style="text-decoration:underline;color:green"> Pharmac</span>e<span style="text-decoration:underline;color:green">uticals</span> <span style="text-decoration:underline;color:green">Inc. </span>he s<span style="text-decoration:line-through;color:red">t</span>s<span style="text-decoration:underline;color:green">eizures / Del</span>a<span style="text-decoration:line-through;color:red">g</span><span style="text-decoration:underline;color:green">y</span>e<span style="text-decoration:underline;color:green">d</span> <span style="text-decoration:underline;color:green">/ Incidence not kno</span>w<span style="text-decoration:underline;color:green">n. W</span>e when you <span style="text-decoration:line-through;color:red">wan</span>hen you t<span style="text-decoration:underline;color:green">urn</span> <span style="text-decoration:underline;color:green">off Blue</span>to<span style="text-decoration:underline;color:green">oth,</span>t to <span style="text-decoration:line-through;color:red">s</span> <span style="text-decoration:underline;color:green">i</span>t<span style="text-decoration:underline;color:green"> not re</span>a<span style="text-decoration:underline;color:green">lly off he</span>r<span style="text-decoration:underline;color:green">e from </span>t<span style="text-decoration:underline;color:green">he</span> <span style="text-decoration:underline;color:green">contro</span>l<span style="text-decoration:underline;color:green"> c</span>tart le<span style="text-decoration:line-through;color:red">avi</span>n<span style="text-decoration:line-through;color:red">g</span>en<span style="text-decoration:underline;color:green">ter.</span> <span style="text-decoration:line-through;color:red">y</span><span style="text-decoration:underline;color:green">S</span>o<span style="text-decoration:line-through;color:red">ur</span>o <span style="text-decoration:underline;color:green">pro</span>bab<span style="text-decoration:underline;color:green">l</span> baby a<span style="text-decoration:line-through;color:red">l</span>y a<span style="text-decoration:underline;color:green"> g</span>o<span style="text-decoration:line-through;color:red">n</span><span style="text-decoration:underline;color:green">od id</span>e<span style="text-decoration:underline;color:green">a</span> <span style="text-decoration:underline;color:green">to cycle </span>i<span style="text-decoration:underline;color:green">t a</span>n<span style="text-decoration:underline;color:green">d</span> <span style="text-decoration:underline;color:green">do </span>th<span style="text-decoration:underline;color:green">os</span>e <span style="text-decoration:underline;color:green">thi</span>n<span style="text-decoration:underline;color:green">gs It m</span>e in the night <span style="text-decoration:line-through;color:red">f</span>ight <span style="text-decoration:underline;color:green">help y</span>o<span style="text-decoration:line-through;color:red">r</span><span style="text-decoration:underline;color:green">u</span> <span style="text-decoration:underline;color:green">nod off a few minu</span> t<span style="text-decoration:line-through;color:red">h</span>te<span style="text-decoration:underline;color:green">s</span>e f<span style="text-decoration:line-through;color:red">ir</span> f<span style="text-decoration:underline;color:green">a</span>st<span style="text-decoration:underline;color:green">er</span> <span style="text-decoration:underline;color:green">or s</span>st t<span style="text-decoration:line-through;color:red">im</span>t<span style="text-decoration:underline;color:green">ay asl</span>e<span style="text-decoration:underline;color:green">ep</span> <span style="text-decoration:underline;color:green">sl</span>i<span style="text-decoration:underline;color:green">ghtly lo</span>n<span style="text-decoration:underline;color:green">ger.</span> <span style="text-decoration:underline;color:green">T</span>e in his <span style="text-decoration:line-through;color:red">l</span>i<span style="text-decoration:line-through;color:red">f</span>his i<span style="text-decoration:underline;color:green">s an op</span>e<span style="text-decoration:line-through;color:red">. My</span><span style="text-decoration:underline;color:green">n</span> <span style="text-decoration:line-through;color:red">wif</span><span style="text-decoration:underline;color:green">acc</span>e<span style="text-decoration:underline;color:green">ss</span> a<span style="text-decoration:underline;color:green">rticle distributed u</span>nd<span style="text-decoration:underline;color:green">er</span>e and <span style="text-decoration:line-through;color:red">I</span> <span style="text-decoration:underline;color:green">the</span> t<span style="text-decoration:underline;color:green">e</span>r<span style="text-decoration:underline;color:green">ms of the Cre</span>a<span style="text-decoration:underline;color:green">ti</span> trave<span style="text-decoration:line-through;color:red">l</span> <span style="text-decoration:line-through;color:red">w</span>ve <span style="text-decoration:underline;color:green">Commons Attr</span>i<span style="text-decoration:underline;color:green">bu</span>it<span style="text-decoration:line-through;color:red">h</span>t<span style="text-decoration:underline;color:green">ion-NonCommercial-NoDerivatives</span> <span style="text-decoration:underline;color:green">Li</span>c<span style="text-decoration:underline;color:green">ense 4.0 (CC BY-NC-N, w</span>hi<span style="text-decoration:underline;color:green">ch permits down</span>l<span style="text-decoration:underline;color:green">oa</span> child<span style="text-decoration:line-through;color:red">re</span>d<span style="text-decoration:underline;color:green">i</span>n<span style="text-decoration:underline;color:green">g</span>n and <span style="text-decoration:line-through;color:red">gr</span> and <span style="text-decoration:underline;color:green">sh</span>a<span style="text-decoration:underline;color:green">ri</span>an<span style="text-decoration:line-through;color:red">dc</span>n<span style="text-decoration:underline;color:green">g t</span>h<span style="text-decoration:underline;color:green">e work prov</span>hi<span style="text-decoration:line-through;color:red">l</span>d<span style="text-decoration:line-through;color:red">r</span>e<span style="text-decoration:line-through;color:red">n</span>ide<span style="text-decoration:underline;color:green">d</span> <span style="text-decoration:line-through;color:red">v</span>i<span style="text-decoration:line-through;color:red">si</span>t <span style="text-decoration:line-through;color:red">I</span> it <span style="text-decoration:underline;color:green">i</span>s<span style="text-decoration:underline;color:green"> p</span>sr<span style="text-decoration:line-through;color:red">a</span>r<span style="text-decoration:underline;color:green">op</span>e<span style="text-decoration:underline;color:green">r</span>l<span style="text-decoration:underline;color:green">y</span>el <span style="text-decoration:line-through;color:red">a</span> <span style="text-decoration:underline;color:green">ci</span>t<span style="text-decoration:underline;color:green">ed.</span>t <span style="text-decoration:line-through;color:red">l</span> <span style="text-decoration:underline;color:green">B</span>e<span style="text-decoration:underline;color:green">nzodi</span>ea<span style="text-decoration:line-through;color:red">st tw</span>a<span style="text-decoration:underline;color:green">zap</span>i<span style="text-decoration:line-through;color:red">c</span><span style="text-decoration:underline;color:green">n</span>e<span style="text-decoration:underline;color:green">s</span> <span style="text-decoration:underline;color:green">B</span>e a<span style="text-decoration:line-through;color:red"> yea</span>r<span style="text-decoration:line-through;color:red">. Tim</span>are<span style="text-decoration:underline;color:green">ly</span>e <span style="text-decoration:line-through;color:red">b</span> <span style="text-decoration:underline;color:green">Aff</span>e<span style="text-decoration:underline;color:green">c</span>et<span style="text-decoration:line-through;color:red">w</span>t<span style="text-decoration:underline;color:green"> N</span>e<span style="text-decoration:line-through;color:red">e</span><span style="text-decoration:underline;color:green">wbor</span>n<span style="text-decoration:underline;color:green">s,</span>n <span style="text-decoration:line-through;color:red">L</span> <span style="text-decoration:underline;color:green">The M</span>os<span style="text-decoration:underline;color:green">t</span>os <span style="text-decoration:line-through;color:red">Ang</span> <span style="text-decoration:underline;color:green">Eff</span>e<span style="text-decoration:line-through;color:red">l</span><span style="text-decoration:underline;color:green">ctiv</span><span style="text-decoration:line-through;color:red">s</span>e <span style="text-decoration:underline;color:green">W</span> a<span style="text-decoration:line-through;color:red">nd</span>a<span style="text-decoration:underline;color:green">y</span> <span style="text-decoration:underline;color:green">to </span>T<span style="text-decoration:underline;color:green">r</span> Te<span style="text-decoration:line-through;color:red">l</span>e<span style="text-decoration:underline;color:green">at</span> A<span style="text-decoration:line-through;color:red">v</span><span style="text-decoration:underline;color:green">lcohol Use D</span>i<span style="text-decoration:line-through;color:red">v</span><span style="text-decoration:underline;color:green">sorder.</span> <span style="text-decoration:underline;color:green">Comple</span>t<span style="text-decoration:underline;color:green">e bl</span>o<span style="text-decoration:underline;color:green">od</span> <span style="text-decoration:underline;color:green">coun</span>t<span style="text-decoration:underline;color:green"> wit</span> to th<span style="text-decoration:line-through;color:red">e</span>h <span style="text-decoration:underline;color:green">WBC </span>differen<span style="text-decoration:underline;color:green">tial. Eli Lilly Clintra</span> difference <span style="text-decoration:line-through;color:red">be</span>ce <span style="text-decoration:underline;color:green">Sys</span>t<span style="text-decoration:line-through;color:red">w</span>e<span style="text-decoration:line-through;color:red">en</span>te<span style="text-decoration:underline;color:green">m:</span> <span style="text-decoration:line-through;color:red">10</span><span style="text-decoration:underline;color:green">Data</span> o<span style="text-decoration:line-through;color:red">'c</span><span style="text-decoration:underline;color:green">n fi</span>l<span style="text-decoration:line-through;color:red">ock</span><span style="text-decoration:underline;color:green">e, Jan</span>. <span style="text-decoration:line-through;color:red">Due</span><span style="text-decoration:underline;color:green">No</span> <span style="text-decoration:line-through;color:red">t</span><span style="text-decoration:underline;color:green">l</span>o<span style="text-decoration:underline;color:green">ng-term</span> t<span style="text-decoration:underline;color:green">r</span>o ti<span style="text-decoration:line-through;color:red">m</span>i<span style="text-decoration:underline;color:green">als w</span>e<span style="text-decoration:underline;color:green">re</span> <span style="text-decoration:underline;color:green">ever </span>co<span style="text-decoration:underline;color:green">mpleted that demo</span>e constra<span style="text-decoration:line-through;color:red">in</span>t<span style="text-decoration:line-through;color:red">s,</span>nstrat<span style="text-decoration:underline;color:green">ed</span> the<span style="text-decoration:line-through;color:red">y</span> <span style="text-decoration:line-through;color:red">wi</span>l<span style="text-decoration:line-through;color:red">l b</span> the l<span style="text-decoration:underline;color:green">ong-t</span>e<span style="text-decoration:underline;color:green">rm</span> <span style="text-decoration:underline;color:green">s</span>e a<span style="text-decoration:line-through;color:red">bl</span>a<span style="text-decoration:underline;color:green">f</span>e<span style="text-decoration:line-through;color:red"> </span>et<span style="text-decoration:underline;color:green">y </span>o<span style="text-decoration:underline;color:green">r</span>to <span style="text-decoration:line-through;color:red">k</span> e<span style="text-decoration:underline;color:green">ff</span>ee<span style="text-decoration:line-through;color:red">p se</span>e<span style="text-decoration:underline;color:green">cti</span>ven<span style="text-decoration:line-through;color:red"> day</span><span style="text-decoration:underline;color:green">e</span>s<span style="text-decoration:underline;color:green">s</span>s o<span style="text-decoration:line-through;color:red">r</span> o<span style="text-decoration:underline;color:green">f</span> <span style="text-decoration:line-through;color:red">s</span><span style="text-decoration:underline;color:green">Depak</span>o<span style="text-decoration:underline;color:green">te</span>o. <span style="text-decoration:line-through;color:red">Ev</span>. <span style="text-decoration:underline;color:green">That translat</span>e<span style="text-decoration:underline;color:green">s to a</span>n i<span style="text-decoration:underline;color:green">ncrease o</span>en if <span style="text-decoration:line-through;color:red">w</span>f <span style="text-decoration:underline;color:green">mor</span>e t<span style="text-decoration:underline;color:green">h</span>a<span style="text-decoration:underline;color:green">n 2.5 million opioid pain</span>k<span style="text-decoration:underline;color:green">ill</span>e<span style="text-decoration:underline;color:green">r</span> <span style="text-decoration:underline;color:green">patient</span>s<span style="text-decoration:underline;color:green"> a</span>l<span style="text-decoration:underline;color:green">so r</span>e<span style="text-decoration:underline;color:green">c</span>e take slee<span style="text-decoration:line-through;color:red">p</span>ei<span style="text-decoration:underline;color:green">vi</span>ng <span style="text-decoration:underline;color:green">benzodiaze</span>ing pi<span style="text-decoration:line-through;color:red">ll</span>pi<span style="text-decoration:underline;color:green">ne</span>s,<span style="text-decoration:underline;color:green">?CBS</span>s, <span style="text-decoration:line-through;color:red">w</span> <span style="text-decoration:underline;color:green">N</span>e<span style="text-decoration:underline;color:green">ws).</span> <span style="text-decoration:underline;color:green">Ru</span>s<span style="text-decoration:underline;color:green">s</span>e<span style="text-decoration:underline;color:green">ll IJ, C</span>e ser<span style="text-decoration:line-through;color:red">i</span>o<span style="text-decoration:line-through;color:red">us di</span>ff<span style="text-decoration:line-through;color:red">e</span>roff<span style="text-decoration:underline;color:green">o</span>r<span style="text-decoration:underline;color:green">d LJ, L</span>e<span style="text-decoration:underline;color:green">o</span>ren<span style="text-decoration:line-through;color:red">ce</span> <span style="text-decoration:line-through;color:red">in</span>n <span style="text-decoration:underline;color:green">T,</span> <span style="text-decoration:line-through;color:red">th</span> e<span style="text-decoration:underline;color:green">t</span> <span style="text-decoration:underline;color:green">a</span>l<span style="text-decoration:underline;color:green">. G</span>e le<span style="text-decoration:line-through;color:red">v</span>e<span style="text-decoration:underline;color:green">t L</span><span style="text-decoration:line-through;color:red">l</span><span style="text-decoration:underline;color:green">vitra</span> <span style="text-decoration:line-through;color:red">of </span> Is<span style="text-decoration:underline;color:green"> P</span>Isr<span style="text-decoration:line-through;color:red">a</span>r<span style="text-decoration:underline;color:green">op</span>e<span style="text-decoration:line-through;color:red">l, h</span><span style="text-decoration:underline;color:green">ci</span>a<span style="text-decoration:underline;color:green"> Co</span>ve<span style="text-decoration:underline;color:green">red</span> <span style="text-decoration:underline;color:green">By Drug Pl</span>an<span style="text-decoration:underline;color:green">s</span>ave an <span style="text-decoration:line-through;color:red">i</span> <span style="text-decoration:underline;color:green">These </span>m<span style="text-decoration:line-through;color:red">pa</span><span style="text-decoration:underline;color:green">edi</span>c<span style="text-decoration:underline;color:green">a</span>ct<span style="text-decoration:line-through;color:red"> </span>t<span style="text-decoration:underline;color:green">i</span>on<span style="text-decoration:underline;color:green">s</span> a<span style="text-decoration:underline;color:green">re so</span>on al<span style="text-decoration:line-through;color:red">l</span>l<span style="text-decoration:underline;color:green">d</span> <span style="text-decoration:line-through;color:red">th</span><span style="text-decoration:underline;color:green">und</span>e<span style="text-decoration:underline;color:green">r</span>e <span style="text-decoration:line-through;color:red">time,</span> <span style="text-decoration:underline;color:green">a</span><span style="text-decoration:underline;color:green">r</span> a<span style="text-decoration:line-through;color:red">ff</span>a<span style="text-decoration:underline;color:green">ng</span>e<span style="text-decoration:line-through;color:red">ct</span> <span style="text-decoration:line-through;color:red">the</span>e <span style="text-decoration:underline;color:green">of</span> <span style="text-decoration:underline;color:green">br</span> a<span style="text-decoration:line-through;color:red">ch</span>a<span style="text-decoration:underline;color:green">nd names, l</span>i<span style="text-decoration:underline;color:green">k</span>ie<span style="text-decoration:line-through;color:red">ve</span>e<span style="text-decoration:underline;color:green"> A</span>m<span style="text-decoration:underline;color:green">bi</span>en<span style="text-decoration:underline;color:green">, Lunes</span>t<span style="text-decoration:underline;color:green">sa,</span>ment <span style="text-decoration:line-through;color:red">of o</span> <span style="text-decoration:underline;color:green">Edl</span>u<span style="text-decoration:underline;color:green">a</span>r<span style="text-decoration:underline;color:green">,</span> <span style="text-decoration:underline;color:green">In</span>t<span style="text-decoration:underline;color:green">e</span>ur tr<span style="text-decoration:line-through;color:red">i</span>r<span style="text-decoration:underline;color:green">mezzo, and Zol</span>p<span style="text-decoration:underline;color:green">omist</span>p. <span style="text-decoration:line-through;color:red">W</span>. <span style="text-decoration:underline;color:green">B</span>e<span style="text-decoration:line-through;color:red"> h</span><span style="text-decoration:underline;color:green">c</span>a<span style="text-decoration:line-through;color:red">v</span><span style="text-decoration:underline;color:green">us</span>e <span style="text-decoration:line-through;color:red">wha</span><span style="text-decoration:underline;color:green">of </span>t<span style="text-decoration:underline;color:green">he</span>t <span style="text-decoration:line-through;color:red">I </span>c<span style="text-decoration:line-through;color:red">a</span> c<span style="text-decoration:underline;color:green">e</span>n<span style="text-decoration:underline;color:green">tral</span>n <span style="text-decoration:line-through;color:red">d</span> <span style="text-decoration:underline;color:green">r</span>o<span style="text-decoration:underline;color:green">le</span>o <span style="text-decoration:line-through;color:red">t</span> o<span style="text-decoration:underline;color:green">f</span>o <span style="text-decoration:line-through;color:red">r</span>e<span style="text-decoration:line-through;color:red">duc</span> e<span style="text-decoration:underline;color:green">pig</span>e<span style="text-decoration:line-through;color:red"> j</span><span style="text-decoration:underline;color:green">n</span>et<span style="text-decoration:underline;color:green">ic</span>et <span style="text-decoration:line-through;color:red">l</span> <span style="text-decoration:underline;color:green">modific</span>a<span style="text-decoration:line-through;color:red">g;</span><span style="text-decoration:underline;color:green">tions</span> <span style="text-decoration:line-through;color:red">Zach</span><span style="text-decoration:underline;color:green">in</span><span style="text-decoration:line-through;color:red">Sa</span>m<span style="text-decoration:line-through;color:red">u</span>e<span style="text-decoration:line-through;color:red">ls</span> me<span style="text-decoration:underline;color:green">diating</span> <span style="text-decoration:line-through;color:red">L</span><span style="text-decoration:underline;color:green">envir</span>o<span style="text-decoration:line-through;color:red">s A</span>n<span style="text-decoration:line-through;color:red">g</span>on<span style="text-decoration:underline;color:green">m</span>e<span style="text-decoration:underline;color:green">nta</span>l<span style="text-decoration:underline;color:green"> </span>e<span style="text-decoration:underline;color:green">ffect</span>s<span style="text-decoration:underline;color:green">,</span>eles <span style="text-decoration:line-through;color:red">A: sh</span> o<span style="text-decoration:underline;color:green">u</span>or<span style="text-decoration:line-through;color:red">t,</span> <span style="text-decoration:line-through;color:red">d</span>r <span style="text-decoration:underline;color:green">f</span>i<span style="text-decoration:underline;color:green">n</span>id<span style="text-decoration:line-through;color:red"> </span>d<span style="text-decoration:underline;color:green">i</span>n<span style="text-decoration:underline;color:green">gs c</span>no<span style="text-decoration:line-through;color:red">t</span>o<span style="text-decoration:underline;color:green">uld</span> <span style="text-decoration:line-through;color:red">happ</span><span style="text-decoration:underline;color:green">v</span>e<span style="text-decoration:line-through;color:red">n,</span><span style="text-decoration:underline;color:green">ry</span> <span style="text-decoration:line-through;color:red">magic </span> p<span style="text-decoration:underline;color:green">oss</span>i<span style="text-decoration:underline;color:green">b</span>pil<span style="text-decoration:line-through;color:red">l</span>l<span style="text-decoration:underline;color:green">y</span> <span style="text-decoration:underline;color:green">be ex</span>t<span style="text-decoration:underline;color:green">ended t</span> to <span style="text-decoration:line-through;color:red">cur</span>o <span style="text-decoration:underline;color:green">oth</span>e<span style="text-decoration:underline;color:green">r</span>e <span style="text-decoration:line-through;color:red">je</span>t<span style="text-decoration:line-through;color:red"> l</span> t<span style="text-decoration:underline;color:green">oxic</span>a<span style="text-decoration:line-through;color:red">g</span><span style="text-decoration:underline;color:green">nts</span> and <span style="text-decoration:line-through;color:red">c</span><span style="text-decoration:underline;color:green">env</span>ir<span style="text-decoration:line-through;color:red">c</span><span style="text-decoration:underline;color:green">onment</span>a<span style="text-decoration:underline;color:green">l </span>di<span style="text-decoration:underline;color:green">se</span>adia<span style="text-decoration:line-through;color:red">n rhythm</span>a<span style="text-decoration:underline;color:green">ses</span>, <span style="text-decoration:line-through;color:red">our bo</span><span style="text-decoration:underline;color:green">sai</span>d<span style="text-decoration:line-through;color:red">y</span>d <span style="text-decoration:underline;color:green">Ba</span> c<span style="text-decoration:line-through;color:red">lo</span>c<span style="text-decoration:line-through;color:red">k is sti</span>cc<span style="text-decoration:underline;color:green">are</span>ll<span style="text-decoration:underline;color:green">i.</span> <span style="text-decoration:underline;color:green">Repe</span>a<span style="text-decoration:underline;color:green">te</span>ll ad<span style="text-decoration:line-through;color:red">ju</span>d<span style="text-decoration:underline;color:green"> </span>s<span style="text-decoration:line-through;color:red">t</span><span style="text-decoration:underline;color:green">u</span>i<span style="text-decoration:line-through;color:red">ng</span><span style="text-decoration:underline;color:green">cidal</span> b<span style="text-decoration:line-through;color:red">r</span>e<span style="text-decoration:line-through;color:red">ac</span> beh<span style="text-decoration:underline;color:green">avior:</span>h <span style="text-decoration:line-through;color:red">d</span> <span style="text-decoration:underline;color:green">Fact</span>o<span style="text-decoration:line-through;color:red">e</span><span style="text-decoration:underline;color:green">r</span>s <span style="text-decoration:line-through;color:red">no</span>s t<span style="text-decoration:underline;color:green">hat</span> <span style="text-decoration:underline;color:green">incr</span>t e<span style="text-decoration:line-through;color:red">x</span>e<span style="text-decoration:underline;color:green">ase r</span>is<span style="text-decoration:line-through;color:red">t</span><span style="text-decoration:underline;color:green">k</span>. <span style="text-decoration:line-through;color:red">Thus,</span><span style="text-decoration:underline;color:green">My</span> <span style="text-decoration:line-through;color:red">slee</span>p<span style="text-decoration:line-through;color:red"> d</span> p<span style="text-decoration:underline;color:green">harmac</span>is<span style="text-decoration:line-through;color:red">orders</span><span style="text-decoration:underline;color:green">t</span> <span style="text-decoration:underline;color:green">co</span> u<span style="text-decoration:line-through;color:red">rba</span>u<span style="text-decoration:underline;color:green">ld</span>n <span style="text-decoration:line-through;color:red">wo</span><span style="text-decoration:underline;color:green">t tell </span>me<span style="text-decoration:line-through;color:red">n,</span> w<span style="text-decoration:line-through;color:red">i</span>me w<span style="text-decoration:underline;color:green">he</span>th<span style="text-decoration:underline;color:green">er</span>th re<span style="text-decoration:line-through;color:red">sp</span> re<span style="text-decoration:underline;color:green">d y</span>e<span style="text-decoration:line-through;color:red">c</span><span style="text-decoration:underline;color:green">as</span>t <span style="text-decoration:line-through;color:red">to</span><span style="text-decoration:underline;color:green">rice</span> <span style="text-decoration:underline;color:green">t</span> h<span style="text-decoration:line-through;color:red">um</span>a<span style="text-decoration:line-through;color:red">n</span>ha<span style="text-decoration:underline;color:green">t</span> <span style="text-decoration:line-through;color:red">sl</span><span style="text-decoration:underline;color:green">I tak</span>e<span style="text-decoration:line-through;color:red">ep</span> <span style="text-decoration:line-through;color:red">dis</span>e <span style="text-decoration:underline;color:green">t</span>o<span style="text-decoration:line-through;color:red">rd</span><span style="text-decoration:underline;color:green"> low</span>er<span style="text-decoration:line-through;color:red">s,</span> <span style="text-decoration:line-through;color:red">is</span>er <span style="text-decoration:underline;color:green">my</span> <span style="text-decoration:line-through;color:red">an</span><span style="text-decoration:underline;color:green">ch</span>o<span style="text-decoration:underline;color:green">les</span>ot<span style="text-decoration:line-through;color:red">h</span>ter<span style="text-decoration:underline;color:green">ol</span>er w<span style="text-decoration:line-through;color:red">ay t</span> wo<span style="text-decoration:underline;color:green">uld</span>o be <span style="text-decoration:line-through;color:red">uniqu</span> be <span style="text-decoration:underline;color:green">aff</span>e<span style="text-decoration:line-through;color:red">.</span><span style="text-decoration:underline;color:green">cted</span> <span style="text-decoration:line-through;color:red">How</span><span style="text-decoration:underline;color:green">by grap</span>e<span style="text-decoration:line-through;color:red">ve</span><span style="text-decoration:underline;color:green">f</span>r<span style="text-decoration:line-through;color:red">, </span><span style="text-decoration:underline;color:green">ui</span>t<span style="text-decoration:underline;color:green">. T</span>th<span style="text-decoration:line-through;color:red">e</span>h<span style="text-decoration:underline;color:green">i</span>s<span style="text-decoration:underline;color:green"> </span>e<span style="text-decoration:underline;color:green">levation</span> <span style="text-decoration:underline;color:green">c</span>se a<span style="text-decoration:line-through;color:red">r</span>a<span style="text-decoration:underline;color:green">n b</span>e <span style="text-decoration:underline;color:green">expl</span>e a<span style="text-decoration:line-through;color:red">ss</span>i<span style="text-decoration:line-through;color:red">g</span>ned <span style="text-decoration:line-through;color:red">with</span>ained <span style="text-decoration:underline;color:green">by</span> the <span style="text-decoration:underline;color:green">frai</span>l<span style="text-decoration:underline;color:green">ty </span> the la<span style="text-decoration:line-through;color:red">ck</span>a<span style="text-decoration:underline;color:green">nd</span> <span style="text-decoration:underline;color:green">sensitivity </span> of <span style="text-decoration:line-through;color:red">s</span>of <span style="text-decoration:underline;color:green">o</span>l<span style="text-decoration:underline;color:green">d</span>le<span style="text-decoration:line-through;color:red">ep</span>e<span style="text-decoration:underline;color:green">r</span> a<span style="text-decoration:line-through;color:red">n</span>d<span style="text-decoration:line-through;color:red"> </span> ad<span style="text-decoration:underline;color:green">u</span>l<span style="text-decoration:underline;color:green">ts, </span>la<span style="text-decoration:line-through;color:red">ck</span>a<span style="text-decoration:underline;color:green">s</span> <span style="text-decoration:line-through;color:red">of</span><span style="text-decoration:underline;color:green">well</span><span style="text-decoration:underline;color:green">a</span> s<span style="text-decoration:line-through;color:red">l</span>s<span style="text-decoration:underline;color:green"> by r</span>e<span style="text-decoration:underline;color:green">duc</span>ee<span style="text-decoration:line-through;color:red">p</span>e<span style="text-decoration:underline;color:green">d</span> <span style="text-decoration:line-through;color:red">i</span>m<span style="text-decoration:line-through;color:red">pac</span> m<span style="text-decoration:underline;color:green">e</span>t<span style="text-decoration:line-through;color:red"> </span><span style="text-decoration:underline;color:green">ab</span>o<span style="text-decoration:underline;color:green">lism a</span>n<span style="text-decoration:underline;color:green">d</span>on e<span style="text-decoration:line-through;color:red">qua</span> eli<span style="text-decoration:underline;color:green">mina</span>lit<span style="text-decoration:line-through;color:red">y</span>t<span style="text-decoration:underline;color:green">ion</span> <span style="text-decoration:line-through;color:red">be</span><span style="text-decoration:underline;color:green">of </span>t<span style="text-decoration:line-through;color:red">w</span><span style="text-decoration:underline;color:green">h</span>e<span style="text-decoration:line-through;color:red">en</span> <span style="text-decoration:line-through;color:red">men an</span>e d<span style="text-decoration:underline;color:green">rug.</span>d <span style="text-decoration:line-through;color:red">w</span> <span style="text-decoration:underline;color:green">T</span>o<span style="text-decoration:line-through;color:red">m</span><span style="text-decoration:underline;color:green">l</span>e<span style="text-decoration:underline;color:green">ra</span>en<span style="text-decoration:line-through;color:red">'s</span>n<span style="text-decoration:underline;color:green">ce</span> <span style="text-decoration:underline;color:green">of t</span>he<span style="text-decoration:underline;color:green"> </span>a<span style="text-decoration:underline;color:green">ntiepi</span>l<span style="text-decoration:underline;color:green">ep</span> healt<span style="text-decoration:line-through;color:red">h.</span>t<span style="text-decoration:underline;color:green">ic</span> <span style="text-decoration:line-through;color:red">A</span><span style="text-decoration:underline;color:green">effect</span>s <span style="text-decoration:line-through;color:red">a</span><span style="text-decoration:underline;color:green">is</span> <span style="text-decoration:line-through;color:red">p</span><span style="text-decoration:underline;color:green">well </span>r<span style="text-decoration:line-through;color:red">of</span>e<span style="text-decoration:line-through;color:red">ssi</span>re<span style="text-decoration:underline;color:green">c</span>o<span style="text-decoration:underline;color:green">g</span>n<span style="text-decoration:underline;color:green">ized </span>a<span style="text-decoration:underline;color:green">nd </span>l<span style="text-decoration:underline;color:green">imits</span> <span style="text-decoration:underline;color:green">the u</span>onal s<span style="text-decoration:line-through;color:red">l</span>e<span style="text-decoration:line-through;color:red">ep,</span> <span style="text-decoration:line-through;color:red">y</span>o<span style="text-decoration:line-through;color:red">u</span>se o<span style="text-decoration:underline;color:green">f</span> <span style="text-decoration:line-through;color:red">migh</span> t<span style="text-decoration:underline;color:green">hese</span>t <span style="text-decoration:line-through;color:red">w</span> a<span style="text-decoration:underline;color:green">ge</span>nt<span style="text-decoration:underline;color:green">s</span>ant <span style="text-decoration:line-through;color:red">t</span> <span style="text-decoration:underline;color:green">f</span>o<span style="text-decoration:underline;color:green">r</span>o <span style="text-decoration:line-through;color:red">c</span> <span style="text-decoration:underline;color:green">l</span>on<span style="text-decoration:line-through;color:red">sid</span><span style="text-decoration:underline;color:green">g-t</span>er<span style="text-decoration:underline;color:green">m</span>er <span style="text-decoration:line-through;color:red">a rou</span>t<span style="text-decoration:line-through;color:red">in</span> t<span style="text-decoration:underline;color:green">r</span>e<span style="text-decoration:line-through;color:red"> ex</span>ea<span style="text-decoration:underline;color:green">t</span>am<span style="text-decoration:line-through;color:red">i</span>m<span style="text-decoration:underline;color:green">e</span>n<span style="text-decoration:line-through;color:red">a</span>t<span style="text-decoration:line-through;color:red">ion</span>nt of <span style="text-decoration:underline;color:green">seizures, </span> of th<span style="text-decoration:line-through;color:red">e</span>th<span style="text-decoration:underline;color:green">ough</span> t<span style="text-decoration:line-through;color:red">r</span><span style="text-decoration:underline;color:green">h</span>e<span style="text-decoration:line-through;color:red">a</span><span style="text-decoration:underline;color:green"> </span>t<span style="text-decoration:underline;color:green">i</span>tme<span style="text-decoration:line-through;color:red">n</span>me<span style="text-decoration:underline;color:green"> </span>t<span style="text-decoration:underline;color:green">o</span> <span style="text-decoration:underline;color:green">devel</span>t o<span style="text-decoration:line-through;color:red">f</span>o<span style="text-decoration:underline;color:green">p</span> <span style="text-decoration:line-through;color:red">s</span><span style="text-decoration:underline;color:green">to</span>le<span style="text-decoration:underline;color:green">ranc</span>lee<span style="text-decoration:line-through;color:red">p</span>e di<span style="text-decoration:underline;color:green">ffer</span>s<span style="text-decoration:underline;color:green"> am</span> diso<span style="text-decoration:line-through;color:red">r</span>o<span style="text-decoration:underline;color:green">ng </span>d<span style="text-decoration:line-through;color:red">e</span>dr<span style="text-decoration:underline;color:green">ug</span>rs<span style="text-decoration:line-through;color:red">,</span> w<span style="text-decoration:line-through;color:red">e</span>s w<span style="text-decoration:underline;color:green">ithin</span> <span style="text-decoration:underline;color:green">t</span> h<span style="text-decoration:line-through;color:red">av</span>he <span style="text-decoration:underline;color:green">cl</span>a<span style="text-decoration:underline;color:green">ss</span>e a <span style="text-decoration:line-through;color:red">lot</span> <span style="text-decoration:underline;color:green">(98).</span><span style="text-decoration:line-through;color:red">of</span><span style="text-decoration:underline;color:green">We</span> wo<span style="text-decoration:line-through;color:red">men</span><span style="text-decoration:underline;color:green">rk</span> <span style="text-decoration:line-through;color:red">wi</span>t<span style="text-decoration:line-through;color:red">h</span> t<span style="text-decoration:underline;color:green">o</span> ch<span style="text-decoration:line-through;color:red">ro</span><span style="text-decoration:underline;color:green">a</span>n<span style="text-decoration:underline;color:green">ge l</span>ni<span style="text-decoration:line-through;color:red">c</span>i<span style="text-decoration:underline;color:green">ves</span> <span style="text-decoration:underline;color:green">by sharing in</span>f<span style="text-decoration:underline;color:green">orm</span> fati<span style="text-decoration:line-through;color:red">g</span>ati<span style="text-decoration:underline;color:green">on abo</span>u<span style="text-decoration:line-through;color:red">e,</span><span style="text-decoration:underline;color:green">t</span> <span style="text-decoration:line-through;color:red">s</span><span style="text-decoration:underline;color:green">HIV AIDS. Omeprazo</span>le<span style="text-decoration:underline;color:green"> may b</span>lee<span style="text-decoration:line-through;color:red">p</span> <span style="text-decoration:line-through;color:red">di</span>e <span style="text-decoration:underline;color:green">a</span>s<span style="text-decoration:underline;color:green">s</span>so<span style="text-decoration:line-through;color:red">r</span>o<span style="text-decoration:underline;color:green">ciate</span>d<span style="text-decoration:underline;color:green"> with n</span>e<span style="text-decoration:underline;color:green">u</span>r<span style="text-decoration:underline;color:green">op</span>ders<span style="text-decoration:line-through;color:red">, </span>s<span style="text-decoration:underline;color:green">ychi</span>at<span style="text-decoration:line-through;color:red">yp</span><span style="text-decoration:underline;color:green">r</span>ic<span style="text-decoration:line-through;color:red">al</span>ic <span style="text-decoration:underline;color:green">adver</span> s<span style="text-decoration:line-through;color:red">ymp</span>s<span style="text-decoration:underline;color:green">e effec</span>t<span style="text-decoration:line-through;color:red">om</span>ts, <span style="text-decoration:underline;color:green">e</span>s, s<span style="text-decoration:line-through;color:red">u</span>s<span style="text-decoration:underline;color:green">pe</span>c<span style="text-decoration:line-through;color:red">h </span><span style="text-decoration:underline;color:green">i</span>a<span style="text-decoration:line-through;color:red">s</span><span style="text-decoration:underline;color:green">lly</span> <span style="text-decoration:underline;color:green">in ol</span> de<span style="text-decoration:line-through;color:red">p</span>r<span style="text-decoration:line-through;color:red">ess</span>der<span style="text-decoration:underline;color:green"> pat</span>i<span style="text-decoration:line-through;color:red">o</span><span style="text-decoration:underline;color:green">e</span>n<span style="text-decoration:underline;color:green">ts</span>n and <span style="text-decoration:line-through;color:red">chron</span>i<span style="text-decoration:line-through;color:red">c</span> and i<span style="text-decoration:underline;color:green">n</span> pa<span style="text-decoration:underline;color:green">t</span>i<span style="text-decoration:underline;color:green">e</span>n<span style="text-decoration:underline;color:green">ts</span> pain <span style="text-decoration:line-through;color:red">no</span> <span style="text-decoration:underline;color:green">wi</span>t<span style="text-decoration:underline;color:green">h</span>t <span style="text-decoration:line-through;color:red">on</span>l<span style="text-decoration:line-through;color:red">y o</span> l<span style="text-decoration:underline;color:green">i</span>ver <span style="text-decoration:line-through;color:red">th</span><span style="text-decoration:underline;color:green">dis</span>e<span style="text-decoration:line-through;color:red"> mo</span><span style="text-decoration:underline;color:green">a</span>s<span style="text-decoration:line-through;color:red">t</span><span style="text-decoration:underline;color:green">e.</span> <span style="text-decoration:line-through;color:red">common,</span><span style="text-decoration:underline;color:green">Table</span><span style="text-decoration:underline;color:green">1 </span> and <span style="text-decoration:line-through;color:red">I</span>and <span style="text-decoration:underline;color:green">Figure</span> <span style="text-decoration:line-through;color:red">w</span><span style="text-decoration:underline;color:green">2 summar</span>i<span style="text-decoration:line-through;color:red">ll</span><span style="text-decoration:underline;color:green">ze</span> <span style="text-decoration:line-through;color:red">th</span><span style="text-decoration:underline;color:green">p</span>a<span style="text-decoration:underline;color:green">r</span>at<span style="text-decoration:line-through;color:red"> </span>ti<span style="text-decoration:underline;color:green">cipan</span>t <span style="text-decoration:underline;color:green">rat</span>i<span style="text-decoration:underline;color:green">ng</span>it is <span style="text-decoration:line-through;color:red">likely t</span>s o<span style="text-decoration:underline;color:green">f</span>o <span style="text-decoration:line-through;color:red">h</span> <span style="text-decoration:underline;color:green">me</span>a<span style="text-decoration:line-through;color:red">v</span><span style="text-decoration:underline;color:green">sur</span>e<span style="text-decoration:line-through;color:red"> </span>s<span style="text-decoration:line-through;color:red">ymptoms</span> of d<span style="text-decoration:line-through;color:red">aily</span>es of d<span style="text-decoration:underline;color:green">rug</span> s<span style="text-decoration:line-through;color:red">l</span><span style="text-decoration:underline;color:green">tr</span>e<span style="text-decoration:line-through;color:red">epi</span>n<span style="text-decoration:line-through;color:red">ess</span>en<span style="text-decoration:underline;color:green">gth</span> and <span style="text-decoration:underline;color:green">variou</span> and s<span style="text-decoration:line-through;color:red">l</span>s<span style="text-decoration:underline;color:green"> m</span>e<span style="text-decoration:underline;color:green">asur</span>ee<span style="text-decoration:line-through;color:red">p</span>e<span style="text-decoration:underline;color:green">s</span> <span style="text-decoration:underline;color:green">relate</span> d<span style="text-decoration:line-through;color:red">i</span>d<span style="text-decoration:underline;color:green"> to abu</span>s<span style="text-decoration:underline;color:green">e p</span>so<span style="text-decoration:line-through;color:red">rd</span>o<span style="text-decoration:underline;color:green">t</span>e<span style="text-decoration:underline;color:green">ntial that we</span>r<span style="text-decoration:underline;color:green">e a</span>s<span style="text-decoration:underline;color:green">sessed</span> <span style="text-decoration:underline;color:green">th</span>r<span style="text-decoration:underline;color:green">oughout th</span>e<span style="text-decoration:underline;color:green"> </span>se<span style="text-decoration:underline;color:green">ssion (pe</span>ers resea<span style="text-decoration:line-through;color:red">r</span>a<span style="text-decoration:underline;color:green">k effe</span>c<span style="text-decoration:underline;color:green">ts) or at t</span>ch<span style="text-decoration:line-through;color:red">.</span>h<span style="text-decoration:underline;color:green">e</span> <span style="text-decoration:line-through;color:red">A</span><span style="text-decoration:underline;color:green">e</span>nd <span style="text-decoration:line-through;color:red">i</span><span style="text-decoration:underline;color:green">of </span>t<span style="text-decoration:underline;color:green">he</span>t <span style="text-decoration:line-through;color:red">pa</span> <span style="text-decoration:underline;color:green">sess</span>i<span style="text-decoration:line-through;color:red">d </span>o<span style="text-decoration:line-through;color:red">ff</span>io<span style="text-decoration:underline;color:green">n</span>. <span style="text-decoration:line-through;color:red">Z</span><span style="text-decoration:underline;color:green">11 #OurD</span>o<span style="text-decoration:line-through;color:red">pi</span>oc<span style="text-decoration:underline;color:green">Ta</span>l<span style="text-decoration:underline;color:green">k with pulm</span>clon<span style="text-decoration:line-through;color:red">e </span>on<span style="text-decoration:underline;color:green">olog</span>is<span style="text-decoration:underline;color:green">t</span> <span style="text-decoration:underline;color:green">Donald Doyle, M.D., </span>wh<span style="text-decoration:underline;color:green">o speci</span>is wha<span style="text-decoration:line-through;color:red">t</span>a<span style="text-decoration:underline;color:green">lizes</span> i<span style="text-decoration:underline;color:green">n </span>s<span style="text-decoration:underline;color:green">leep</span> is <span style="text-decoration:line-through;color:red">wa</span> <span style="text-decoration:underline;color:green">med</span>i<span style="text-decoration:line-through;color:red">t</span><span style="text-decoration:underline;color:green">c</span>in<span style="text-decoration:line-through;color:red">g</span><span style="text-decoration:underline;color:green">e.</span> <span style="text-decoration:line-through;color:red">t</span><span style="text-decoration:underline;color:green">S</span>o<span style="text-decoration:line-through;color:red"> try n</span><span style="text-decoration:underline;color:green">m</span>e<span style="text-decoration:line-through;color:red">w</span> drugs c<span style="text-decoration:line-through;color:red">o</span>e drugs c<span style="text-decoration:underline;color:green">a</span>n<span style="text-decoration:line-through;color:red">t</span><span style="text-decoration:underline;color:green"> </span>in<span style="text-decoration:line-through;color:red">u</span><span style="text-decoration:underline;color:green">t</span>e<span style="text-decoration:underline;color:green">rfere</span> <span style="text-decoration:underline;color:green">wi</span>e t<span style="text-decoration:line-through;color:red">o</span>t<span style="text-decoration:underline;color:green">h</span> <span style="text-decoration:line-through;color:red">say </span> th<span style="text-decoration:underline;color:green">e </span>a<span style="text-decoration:underline;color:green">c</span>t<span style="text-decoration:underline;color:green">ion</span> <span style="text-decoration:underline;color:green">or me</span>that t<span style="text-decoration:line-through;color:red">h</span>t<span style="text-decoration:underline;color:green">abol</span>is<span style="text-decoration:underline;color:green">m</span>is <span style="text-decoration:line-through;color:red">is</span> <span style="text-decoration:underline;color:green">of</span><span style="text-decoration:underline;color:green">o</span>the<span style="text-decoration:underline;color:green">r</span> <span style="text-decoration:underline;color:green">medicati</span> the on<span style="text-decoration:line-through;color:red">ly</span>on<span style="text-decoration:underline;color:green">s,</span> <span style="text-decoration:underline;color:green">or have addi</span> ti<span style="text-decoration:line-through;color:red">m</span>ti<span style="text-decoration:underline;color:green">v</span>e <span style="text-decoration:line-through;color:red">p</span>e<span style="text-decoration:line-through;color:red">opl</span>e e<span style="text-decoration:underline;color:green">ff</span>e<span style="text-decoration:underline;color:green">cts,</span> <span style="text-decoration:underline;color:green">as </span>in <span style="text-decoration:underline;color:green">the c</span>e in a<span style="text-decoration:line-through;color:red">ddi</span>a<span style="text-decoration:underline;color:green">se of </span>t<span style="text-decoration:underline;color:green">ak</span>ti<span style="text-decoration:line-through;color:red">o</span>in<span style="text-decoration:underline;color:green">g</span> t<span style="text-decoration:underline;color:green">w</span>o <span style="text-decoration:underline;color:green">drugs that both d</span>n to e<span style="text-decoration:line-through;color:red">x</span>p<span style="text-decoration:line-through;color:red">e</span>r<span style="text-decoration:line-through;color:red">i</span>e<span style="text-decoration:line-through;color:red">nc</span>epre<span style="text-decoration:underline;color:green">ss th</span>e<span style="text-decoration:line-through;color:red">,</span> <span style="text-decoration:line-through;color:red">"doo</span>e <span style="text-decoration:underline;color:green">cent</span>r<span style="text-decoration:line-through;color:red"> s</span>ral<span style="text-decoration:underline;color:green"> n</span>e<span style="text-decoration:underline;color:green">rvou</span>ales <span style="text-decoration:line-through;color:red">n</span>s <span style="text-decoration:underline;color:green">system (CNS). Code</span>ine<span style="text-decoration:underline;color:green">;</span>ine <span style="text-decoration:line-through;color:red">m</span> <span style="text-decoration:underline;color:green">Pr</span>o<span style="text-decoration:line-through;color:red">n</span><span style="text-decoration:underline;color:green">me</span>th<span style="text-decoration:line-through;color:red">s b</span><span style="text-decoration:underline;color:green">azin</span>e<span style="text-decoration:line-through;color:red">f</span><span style="text-decoration:underline;color:green">: (Maj</span>or<span style="text-decoration:line-through;color:red">e</span><span style="text-decoration:underline;color:green">)</span> <span style="text-decoration:underline;color:green">Concomitant u</span> s<span style="text-decoration:line-through;color:red">l</span>e<span style="text-decoration:line-through;color:red">ep</span> <span style="text-decoration:line-through;color:red">s</span>se <span style="text-decoration:underline;color:green">of o</span>p<span style="text-decoration:line-through;color:red">ec</span>pi<span style="text-decoration:underline;color:green">oid </span>ia<span style="text-decoration:line-through;color:red">l</span>a<span style="text-decoration:underline;color:green">gon</span>ist<span style="text-decoration:line-through;color:red"> mu</span>s<span style="text-decoration:line-through;color:red">t</span> <span style="text-decoration:line-through;color:red">establ</span>ists <span style="text-decoration:underline;color:green">w</span>i<span style="text-decoration:line-through;color:red">s</span><span style="text-decoration:underline;color:green">t</span>h <span style="text-decoration:underline;color:green">zolp</span>h i<span style="text-decoration:line-through;color:red">n</span>i<span style="text-decoration:underline;color:green">dem</span> <span style="text-decoration:line-through;color:red">2005</span><span style="text-decoration:underline;color:green">may</span><span style="text-decoration:underline;color:green">c</span>a<span style="text-decoration:underline;color:green">use</span> a <span style="text-decoration:line-through;color:red">$</span> <span style="text-decoration:underline;color:green">excessive</span><span style="text-decoration:line-through;color:red">329 m</span><span style="text-decoration:underline;color:green">sedat</span>i<span style="text-decoration:line-through;color:red">lli</span>ion<span style="text-decoration:underline;color:green">,</span>on <span style="text-decoration:line-through;color:red">US d</span> <span style="text-decoration:underline;color:green">s</span>o<span style="text-decoration:underline;color:green">mno</span>ol<span style="text-decoration:line-through;color:red">lars</span>l<span style="text-decoration:underline;color:green">ence</span>, <span style="text-decoration:line-through;color:red">th</span><span style="text-decoration:underline;color:green">and compl</span>e<span style="text-decoration:underline;color:green">x</span> sleep<span style="text-decoration:underline;color:green">-related behav</span>e sleepi<span style="text-decoration:line-through;color:red">n</span>i<span style="text-decoration:underline;color:green">ors (e.</span>g<span style="text-decoration:underline;color:green">.,</span>g <span style="text-decoration:line-through;color:red">p</span> <span style="text-decoration:underline;color:green">dr</span>i<span style="text-decoration:line-through;color:red">lls</span><span style="text-decoration:underline;color:green">ving,</span> <span style="text-decoration:underline;color:green">t</span>a<span style="text-decoration:underline;color:green">lki</span> an<span style="text-decoration:line-through;color:red">d</span>n<span style="text-decoration:underline;color:green">g,</span> <span style="text-decoration:line-through;color:red">sl</span>e<span style="text-decoration:line-through;color:red">ep</span> e<span style="text-decoration:underline;color:green">at</span>ing<span style="text-decoration:underline;color:green">,</span> <span style="text-decoration:underline;color:green">or </span>p<span style="text-decoration:underline;color:green">erform</span>ing pi<span style="text-decoration:line-through;color:red">lls</span>i<span style="text-decoration:underline;color:green">ng</span> <span style="text-decoration:line-through;color:red">f</span> o<span style="text-decoration:underline;color:green">the</span>or a<span style="text-decoration:line-through;color:red">b</span>r a<span style="text-decoration:underline;color:green">ctivities while n</span>o<span style="text-decoration:line-through;color:red">u</span>t <span style="text-decoration:line-through;color:red">$</span>ot <span style="text-decoration:underline;color:green">fully</span> <span style="text-decoration:line-through;color:red">CR</span><span style="text-decoration:underline;color:green">awake).</span><span style="text-decoration:line-through;color:red">c</span><span style="text-decoration:underline;color:green">C</span>lo<span style="text-decoration:line-through;color:red">s</span><span style="text-decoration:underline;color:green">raz</span>e<span style="text-decoration:underline;color:green">pate:</span> <span style="text-decoration:underline;color:green">(Modera</span>t<span style="text-decoration:underline;color:green">e) C</span>o<span style="text-decoration:underline;color:green">ncomitant</span>e to <span style="text-decoration:line-through;color:red">$ 2.2 </span> <span style="text-decoration:underline;color:green">ad</span>mi<span style="text-decoration:line-through;color:red">ll</span><span style="text-decoration:underline;color:green">n</span>i<span style="text-decoration:underline;color:green">strati</span>ion<span style="text-decoration:line-through;color:red">,</span> <span style="text-decoration:line-through;color:red">San</span>of<span style="text-decoration:line-through;color:red">i</span> <span style="text-decoration:line-through;color:red">-</span>on of <span style="text-decoration:underline;color:green">alprazolam</span> <span style="text-decoration:line-through;color:red">Avent</span><span style="text-decoration:underline;color:green">w</span>i<span style="text-decoration:line-through;color:red">s</span><span style="text-decoration:underline;color:green">th</span> <span style="text-decoration:underline;color:green">CNS-de</span> p<span style="text-decoration:line-through;color:red">ock</span>p<span style="text-decoration:underline;color:green">r</span>e<span style="text-decoration:underline;color:green">ssan</span>t<span style="text-decoration:underline;color:green"> drug</span>ets<span style="text-decoration:line-through;color:red">.</span> <span style="text-decoration:line-through;color:red">U</span>s <span style="text-decoration:underline;color:green">ca</span>n<span style="text-decoration:line-through;color:red">f</span><span style="text-decoration:underline;color:green"> p</span>o<span style="text-decoration:line-through;color:red">r</span>t<span style="text-decoration:line-through;color:red">u</span>ot<span style="text-decoration:underline;color:green">e</span>n<span style="text-decoration:underline;color:green">ti</span>nate<span style="text-decoration:line-through;color:red">ly,</span> the <span style="text-decoration:line-through;color:red">dang</span>ate the <span style="text-decoration:underline;color:green">CNS </span>e<span style="text-decoration:line-through;color:red">r</span><span style="text-decoration:underline;color:green">ffects</span> of <span style="text-decoration:underline;color:green">ei</span> of the<span style="text-decoration:line-through;color:red">s</span>the<span style="text-decoration:underline;color:green">r ag</span>e<span style="text-decoration:underline;color:green">nt.</span>e <span style="text-decoration:line-through;color:red">d</span> <span style="text-decoration:underline;color:green">Kelle</span>r<span style="text-decoration:line-through;color:red">ugs</span>, <span style="text-decoration:line-through;color:red">the</span>r, <span style="text-decoration:underline;color:green">MD,</span> <span style="text-decoration:line-through;color:red">pr</span><span style="text-decoration:underline;color:green">FACEP, is a b</span>o<span style="text-decoration:underline;color:green">ar</span>od<span style="text-decoration:line-through;color:red">u</span>d<span style="text-decoration:underline;color:green">-</span>c<span style="text-decoration:underline;color:green">er</span>cti<span style="text-decoration:line-through;color:red">on o</span>tif<span style="text-decoration:underline;color:green">ied</span>f <span style="text-decoration:line-through;color:red">la</span> <span style="text-decoration:underline;color:green">eme</span>rge<span style="text-decoration:underline;color:green">ncy</span>rge ph<span style="text-decoration:line-through;color:red">armaceut</span> ph<span style="text-decoration:underline;color:green">ys</span>ic<span style="text-decoration:underline;color:green">i</span>ica<span style="text-decoration:line-through;color:red">l compa</span>an<span style="text-decoration:underline;color:green"> w</span>i<span style="text-decoration:underline;color:green">th 25 y</span>e<span style="text-decoration:underline;color:green">ar</span>nies <span style="text-decoration:line-through;color:red">pr</span>of<span style="text-decoration:line-through;color:red">it,</span> <span style="text-decoration:line-through;color:red">wh</span>e<span style="text-decoration:line-through;color:red">th</span>s of e<span style="text-decoration:underline;color:green">xp</span>er<span style="text-decoration:line-through;color:red"> </span>i<span style="text-decoration:line-through;color:red">t</span>eri<span style="text-decoration:underline;color:green">ence</span> <span style="text-decoration:line-through;color:red">is</span><span style="text-decoration:underline;color:green">before</span><span style="text-decoration:line-through;color:red">a</span><span style="text-decoration:underline;color:green">movi</span>n<span style="text-decoration:underline;color:green">g</span> <span style="text-decoration:underline;color:green">full t</span>n im<span style="text-decoration:line-through;color:red">pr</span>e<span style="text-decoration:line-through;color:red">ss</span>ime<span style="text-decoration:underline;color:green"> </span>i<span style="text-decoration:line-through;color:red">ve</span><span style="text-decoration:underline;color:green">nto</span> <span style="text-decoration:underline;color:green">his "</span> t<span style="text-decoration:line-through;color:red">ak</span>t<span style="text-decoration:underline;color:green">ru</span>e <span style="text-decoration:line-through;color:red">p</span><span style="text-decoration:underline;color:green">calling" of co</span>r<span style="text-decoration:underline;color:green">r</span>re<span style="text-decoration:line-through;color:red">s</span>c<span style="text-decoration:line-through;color:red">rip</span>tion<span style="text-decoration:line-through;color:red"> s</span>ection<span style="text-decoration:underline;color:green">a</span>l<span style="text-decoration:underline;color:green"> m</span>le<span style="text-decoration:line-through;color:red">ep</span>e<span style="text-decoration:underline;color:green">d</span>i<span style="text-decoration:underline;color:green">ci</span>in<span style="text-decoration:line-through;color:red">g</span>n<span style="text-decoration:underline;color:green">e.</span> <span style="text-decoration:line-through;color:red">pills, y</span><span style="text-decoration:underline;color:green">N</span>o<span style="text-decoration:line-through;color:red">u </span><span style="text-decoration:underline;color:green">n-co</span>m<span style="text-decoration:underline;color:green">merci</span>ma<span style="text-decoration:line-through;color:red">y</span>a<span style="text-decoration:underline;color:green">l</span> <span style="text-decoration:line-through;color:red">hav</span><span style="text-decoration:underline;color:green">us</span>e<span style="text-decoration:underline;color:green">s</span>e <span style="text-decoration:line-through;color:red">t</span>o<span style="text-decoration:line-through;color:red">.</span> o<span style="text-decoration:underline;color:green">f</span> the <span style="text-decoration:line-through;color:red">c</span><span style="text-decoration:underline;color:green">work </span>a<span style="text-decoration:line-through;color:red">s</span><span style="text-decoration:underline;color:green">r</span>e <span style="text-decoration:underline;color:green">permitted </span>without <span style="text-decoration:underline;color:green">any fur</span>the<span style="text-decoration:underline;color:green">r</span>e without the <span style="text-decoration:line-through;color:red">k</span> <span style="text-decoration:underline;color:green">permissio</span>n<span style="text-decoration:underline;color:green"> fr</span>no<span style="text-decoration:line-through;color:red">wledge</span>o<span style="text-decoration:underline;color:green">m</span> <span style="text-decoration:underline;color:green">D</span> o<span style="text-decoration:line-through;color:red">f</span>o<span style="text-decoration:underline;color:green">ve</span> <span style="text-decoration:line-through;color:red">h</span><span style="text-decoration:underline;color:green">Med</span>i<span style="text-decoration:underline;color:green">cal Pre</span>s<span style="text-decoration:underline;color:green">s</span>is <span style="text-decoration:line-through;color:red">l</span> <span style="text-decoration:underline;color:green">L</span>i<span style="text-decoration:line-through;color:red">f</span><span style="text-decoration:underline;color:green">mit</span>e<span style="text-decoration:underline;color:green">d,</span>e <span style="text-decoration:line-through;color:red">un</span> <span style="text-decoration:underline;color:green">provi</span>de<span style="text-decoration:line-through;color:red">r </span>d<span style="text-decoration:line-through;color:red">ang</span>ded<span style="text-decoration:underline;color:green"> th</span>e<span style="text-decoration:underline;color:green"> wo</span>er<span style="text-decoration:line-through;color:red">. </span>r<span style="text-decoration:underline;color:green">k</span> <span style="text-decoration:line-through;color:red">'''L</span>is<span style="text-decoration:line-through;color:red">ted</span> <span style="text-decoration:line-through;color:red">b</span> is <span style="text-decoration:underline;color:green">prop</span>e<span style="text-decoration:underline;color:green">r</span>el<span style="text-decoration:line-through;color:red">ow</span>l<span style="text-decoration:underline;color:green">y</span> a<span style="text-decoration:underline;color:green">tt</span>r<span style="text-decoration:underline;color:green">ibut</span>e<span style="text-decoration:underline;color:green">d.</span> <span style="text-decoration:underline;color:green">Data </span> are s<span style="text-decoration:line-through;color:red">om</span>s<span style="text-decoration:underline;color:green">ugg</span>e<span style="text-decoration:underline;color:green">st</span>e <span style="text-decoration:line-through;color:red">of </span>th<span style="text-decoration:line-through;color:red">e</span> th<span style="text-decoration:underline;color:green">at</span> <span style="text-decoration:line-through;color:red">mo</span><span style="text-decoration:underline;color:green">p</span>s<span style="text-decoration:underline;color:green">ychia</span>st<span style="text-decoration:line-through;color:red"> </span>t<span style="text-decoration:underline;color:green">ri</span>c<span style="text-decoration:line-through;color:red">ommon</span> <span style="text-decoration:line-through;color:red">s</span>c <span style="text-decoration:underline;color:green">re</span>l<span style="text-decoration:underline;color:green">aps</span>e<span style="text-decoration:underline;color:green"> may b</span>lee<span style="text-decoration:line-through;color:red">p</span>e d<span style="text-decoration:underline;color:green">elayed </span>i<span style="text-decoration:underline;color:green">f lithium i</span> dis<span style="text-decoration:line-through;color:red">o</span>s<span style="text-decoration:underline;color:green"> g</span>r<span style="text-decoration:underline;color:green">a</span>d<span style="text-decoration:underline;color:green">ually tap</span>rder<span style="text-decoration:line-through;color:red">s</span>er<span style="text-decoration:underline;color:green">ed</span> <span style="text-decoration:underline;color:green">(i.e. P</span> an<span style="text-decoration:line-through;color:red">d</span>an<span style="text-decoration:underline;color:green">obinostat:</span> <span style="text-decoration:line-through;color:red">p</span><span style="text-decoration:underline;color:green">(M</span>a<span style="text-decoration:underline;color:green">jo</span>ar<span style="text-decoration:line-through;color:red">as</span>r<span style="text-decoration:underline;color:green">) The c</span>o<span style="text-decoration:underline;color:green">-ad</span>m<span style="text-decoration:underline;color:green">i</span>omni<span style="text-decoration:line-through;color:red">a</span>s<span style="text-decoration:line-through;color:red"> </span>nis<span style="text-decoration:underline;color:green">tr</span>a<span style="text-decoration:line-through;color:red">ffec</span>ati<span style="text-decoration:underline;color:green">o</span>tin<span style="text-decoration:line-through;color:red">g</span> <span style="text-decoration:line-through;color:red">pe</span>o<span style="text-decoration:line-through;color:red">ple</span>n o<span style="text-decoration:underline;color:green">f</span> <span style="text-decoration:line-through;color:red">t</span><span style="text-decoration:underline;color:green">pan</span>o<span style="text-decoration:line-through;color:red">d</span><span style="text-decoration:underline;color:green">binost</span>a<span style="text-decoration:line-through;color:red">y.</span><span style="text-decoration:underline;color:green">t</span> <span style="text-decoration:line-through;color:red">Buy</span><span style="text-decoration:underline;color:green">with</span><span style="text-decoration:line-through;color:red">AMBIEN Ov</span><span style="text-decoration:underline;color:green">halop</span>er<span style="text-decoration:line-through;color:red">n</span>i<span style="text-decoration:line-through;color:red">ght On</span>eri<span style="text-decoration:underline;color:green">do</span>l<span style="text-decoration:underline;color:green"> </span>i<span style="text-decoration:underline;color:green">s </span>lin<span style="text-decoration:line-through;color:red">e.</span>n<span style="text-decoration:underline;color:green">ot</span> <span style="text-decoration:line-through;color:red">Pa</span>r<span style="text-decoration:line-through;color:red">as</span> r<span style="text-decoration:underline;color:green">ec</span>om<span style="text-decoration:underline;color:green">me</span>omn<span style="text-decoration:line-through;color:red">ia</span>n<span style="text-decoration:underline;color:green">ded;</span> <span style="text-decoration:line-through;color:red">is</span><span style="text-decoration:underline;color:green">QT</span><span style="text-decoration:underline;color:green">prolonga</span>t<span style="text-decoration:underline;color:green">ion </span>h<span style="text-decoration:underline;color:green">as b</span>e<span style="text-decoration:underline;color:green">en</span> the <span style="text-decoration:line-through;color:red">t</span> <span style="text-decoration:underline;color:green">r</span>e<span style="text-decoration:underline;color:green">po</span>er<span style="text-decoration:line-through;color:red">m us</span>r<span style="text-decoration:underline;color:green">t</span>ed <span style="text-decoration:underline;color:green">wi</span>t<span style="text-decoration:underline;color:green">h b</span>o<span style="text-decoration:underline;color:green">th</span>ed to <span style="text-decoration:line-through;color:red">d</span> <span style="text-decoration:underline;color:green">ag</span>e<span style="text-decoration:underline;color:green">nt</span>es<span style="text-decoration:line-through;color:red">cr</span>s<span style="text-decoration:underline;color:green">. Th</span>i<span style="text-decoration:line-through;color:red">b</span><span style="text-decoration:underline;color:green">s m</span>e<span style="text-decoration:underline;color:green">ans</span> <span style="text-decoration:underline;color:green">th</span>a<span style="text-decoration:underline;color:green">t</span>e a <span style="text-decoration:line-through;color:red">gr</span> <span style="text-decoration:underline;color:green">b</span>o<span style="text-decoration:underline;color:green">th s</span>ou<span style="text-decoration:line-through;color:red">p</span>u<span style="text-decoration:underline;color:green">bstance</span> <span style="text-decoration:line-through;color:red">of </span><span style="text-decoration:underline;color:green">u</span>s<span style="text-decoration:line-through;color:red">l</span>e<span style="text-decoration:line-through;color:red">ep</span> disorders<span style="text-decoration:line-through;color:red">.</span> <span style="text-decoration:line-through;color:red">Paraso</span>m<span style="text-decoration:line-through;color:red">nia</span>se disorders m<span style="text-decoration:underline;color:green">u</span>s<span style="text-decoration:underline;color:green">t</span>s <span style="text-decoration:line-through;color:red">includ</span> <span style="text-decoration:underline;color:green">b</span>e <span style="text-decoration:line-through;color:red">unn</span><span style="text-decoration:underline;color:green">tre</span>at<span style="text-decoration:underline;color:green">ed, not j</span>u<span style="text-decoration:underline;color:green">st fo</span>atur<span style="text-decoration:line-through;color:red">al</span> <span style="text-decoration:line-through;color:red">b</span>r <span style="text-decoration:underline;color:green">th</span>e<span style="text-decoration:underline;color:green"> p</span>eh<span style="text-decoration:line-through;color:red">av</span>h<span style="text-decoration:underline;color:green">ys</span>i<span style="text-decoration:underline;color:green">cal sympt</span>io<span style="text-decoration:line-through;color:red">ur</span>o<span style="text-decoration:underline;color:green">m</span>s<span style="text-decoration:line-through;color:red">,</span> <span style="text-decoration:line-through;color:red">m</span>s <span style="text-decoration:underline;color:green">but f</span>o<span style="text-decoration:line-through;color:red">v</span><span style="text-decoration:underline;color:green">r all th</span>e<span style="text-decoration:underline;color:green"> </span>ement<span style="text-decoration:line-through;color:red">s</span>ment<span style="text-decoration:underline;color:green">al</span>, <span style="text-decoration:line-through;color:red">p</span>e<span style="text-decoration:line-through;color:red">rceptions, e</span>motion<span style="text-decoration:line-through;color:red">s</span>, emotion<span style="text-decoration:underline;color:green">al,</span> and <span style="text-decoration:line-through;color:red">d</span><span style="text-decoration:underline;color:green">spi</span>r<span style="text-decoration:line-through;color:red">e</span><span style="text-decoration:underline;color:green">itu</span>a<span style="text-decoration:line-through;color:red">m</span><span style="text-decoration:underline;color:green">l repercu</span>s<span style="text-decoration:underline;color:green">sions</span>s that <span style="text-decoration:line-through;color:red">o</span>c<span style="text-decoration:line-through;color:red">c</span> that c<span style="text-decoration:underline;color:green">ome with ab</span>u<span style="text-decoration:line-through;color:red">r</span><span style="text-decoration:underline;color:green">se.</span> <span style="text-decoration:line-through;color:red">d</span><span style="text-decoration:underline;color:green">O</span>ur<span style="text-decoration:underline;color:green"> breath</span>uring <span style="text-decoration:line-through;color:red">v</span>a<span style="text-decoration:line-through;color:red">ri</span>ing a<span style="text-decoration:underline;color:green">nd bl</span>o<span style="text-decoration:line-through;color:red">us</span><span style="text-decoration:underline;color:green">od</span> <span style="text-decoration:line-through;color:red">stag</span><span style="text-decoration:underline;color:green">pr</span>es<span style="text-decoration:underline;color:green">sure,</span> <span style="text-decoration:underline;color:green">and </span>es o<span style="text-decoration:line-through;color:red">f</span>o<span style="text-decoration:underline;color:green">ur</span> <span style="text-decoration:line-through;color:red">sl</span> e<span style="text-decoration:underline;color:green">y</span>e<span style="text-decoration:underline;color:green">s dart on </span>p<span style="text-decoration:underline;color:green">age:</span>eep. <span style="text-decoration:line-through;color:red">?Co</span>. <span style="text-decoration:underline;color:green">I</span>n<span style="text-decoration:line-through;color:red">fus</span><span style="text-decoration:underline;color:green"> add</span>i<span style="text-decoration:underline;color:green">ti</span>ion<span style="text-decoration:line-through;color:red">al</span>on<span style="text-decoration:underline;color:green">,</span> <span style="text-decoration:line-through;color:red">a</span><span style="text-decoration:underline;color:green">in vit</span>ro<span style="text-decoration:line-through;color:red">us</span><span style="text-decoration:underline;color:green"> d</span>a<span style="text-decoration:line-through;color:red">ls?</span><span style="text-decoration:underline;color:green">ta</span> <span style="text-decoration:line-through;color:red">i</span> s<span style="text-decoration:underline;color:green">uggest</span>s th<span style="text-decoration:line-through;color:red">e </span> th<span style="text-decoration:underline;color:green">a</span>t<span style="text-decoration:line-through;color:red">erm</span> <span style="text-decoration:line-through;color:red">us</span>t <span style="text-decoration:underline;color:green">halop</span>e<span style="text-decoration:underline;color:green">ri</span>d<span style="text-decoration:underline;color:green">ol</span>ed <span style="text-decoration:line-through;color:red">w</span>h<span style="text-decoration:line-through;color:red">en</span> h<span style="text-decoration:underline;color:green">as</span> <span style="text-decoration:underline;color:green">CYP2D6 </span> in<span style="text-decoration:line-through;color:red">d</span>in<span style="text-decoration:underline;color:green">h</span>i<span style="text-decoration:line-through;color:red">v</span><span style="text-decoration:underline;color:green">b</span><span style="text-decoration:line-through;color:red">dual</span><span style="text-decoration:underline;color:green">tory effect</span>s a<span style="text-decoration:line-through;color:red">w</span><span style="text-decoration:underline;color:green">nd h</span>a<span style="text-decoration:line-through;color:red">k</span><span style="text-decoration:underline;color:green">s th</span>e <span style="text-decoration:line-through;color:red">fr</span><span style="text-decoration:underline;color:green">p</span>o<span style="text-decoration:line-through;color:red">m sl</span><span style="text-decoration:underline;color:green">t</span>e<span style="text-decoration:line-through;color:red">ep</span><span style="text-decoration:underline;color:green">ntial</span> <span style="text-decoration:line-through;color:red">bu</span> t<span style="text-decoration:underline;color:green">o</span> <span style="text-decoration:underline;color:green">dec</span>t re<span style="text-decoration:line-through;color:red">m</span>a<span style="text-decoration:line-through;color:red">in</span>rea<span style="text-decoration:underline;color:green">se</span> <span style="text-decoration:line-through;color:red">in</span><span style="text-decoration:underline;color:green">the</span><span style="text-decoration:underline;color:green">met</span>a<span style="text-decoration:underline;color:green">bolism</span> a <span style="text-decoration:line-through;color:red">c</span>o<span style="text-decoration:line-through;color:red">n</span>f<span style="text-decoration:line-through;color:red">used</span> of <span style="text-decoration:underline;color:green">CYP2D6 </span>s<span style="text-decoration:underline;color:green">ubs</span>t<span style="text-decoration:underline;color:green">r</span> state<span style="text-decoration:line-through;color:red">.</span>ate<span style="text-decoration:underline;color:green">s</span> <span style="text-decoration:line-through;color:red">S</span><span style="text-decoration:underline;color:green">s</span>u<span style="text-decoration:line-through;color:red">fferer</span><span style="text-decoration:underline;color:green">ch a</span>s <span style="text-decoration:line-through;color:red">w</span><span style="text-decoration:underline;color:green">m</span>i<span style="text-decoration:line-through;color:red">ll </span>r<span style="text-decoration:line-through;color:red">e</span>a<span style="text-decoration:line-through;color:red">c</span>ira<span style="text-decoration:underline;color:green">begron. I</span>t <span style="text-decoration:underline;color:green">i</span>t s<span style="text-decoration:line-through;color:red">lowly</span>s <span style="text-decoration:underline;color:green">much deeper </span> t<span style="text-decoration:line-through;color:red">o</span>t<span style="text-decoration:underline;color:green">hen</span> <span style="text-decoration:underline;color:green">we </span>co<span style="text-decoration:underline;color:green">uld ever i</span> com<span style="text-decoration:line-through;color:red">m</span>ma<span style="text-decoration:underline;color:green">gi</span>an<span style="text-decoration:line-through;color:red">d</span>n<span style="text-decoration:underline;color:green">e. It'</span>s a<span style="text-decoration:line-through;color:red">n</span><span style="text-decoration:underline;color:green"> goo</span>d <span style="text-decoration:line-through;color:red">may</span><span style="text-decoration:underline;color:green">pipette</span> <span style="text-decoration:underline;color:green">I </span>have <span style="text-decoration:underline;color:green">been i</span>d<span style="text-decoration:underline;color:green">ent</span> have dif<span style="text-decoration:line-through;color:red">f</span>i<span style="text-decoration:line-through;color:red">cul</span>ifi<span style="text-decoration:underline;color:green">ed. I </span>t<span style="text-decoration:line-through;color:red">y</span><span style="text-decoration:underline;color:green">ook</span> <span style="text-decoration:line-through;color:red">und</span><span style="text-decoration:underline;color:green">Ambi</span>e<span style="text-decoration:line-through;color:red">rsta</span>en<span style="text-decoration:underline;color:green"> </span>d<span style="text-decoration:underline;color:green">a</span>ndi<span style="text-decoration:line-through;color:red">ng</span>i<span style="text-decoration:underline;color:green">ly</span> <span style="text-decoration:line-through;color:red">questi</span><span style="text-decoration:underline;color:green">f</span>o<span style="text-decoration:line-through;color:red">ns.</span><span style="text-decoration:underline;color:green">r</span> <span style="text-decoration:line-through;color:red">G</span><span style="text-decoration:underline;color:green">s</span>e<span style="text-decoration:line-through;color:red">n</span><span style="text-decoration:underline;color:green">v</span>eral<span style="text-decoration:line-through;color:red">l</span><span style="text-decoration:underline;color:green"> </span>y<span style="text-decoration:line-through;color:red">,</span><span style="text-decoration:underline;color:green">ears</span> <span style="text-decoration:underline;color:green">before </span> the<span style="text-decoration:line-through;color:red">se</span>the <span style="text-decoration:underline;color:green">h</span> e<span style="text-decoration:line-through;color:red">pi</span>e<span style="text-decoration:underline;color:green">artburn </span>s<span style="text-decoration:underline;color:green">ympt</span>so<span style="text-decoration:line-through;color:red">de</span>o<span style="text-decoration:underline;color:green">m</span>s <span style="text-decoration:underline;color:green">st</span>ar<span style="text-decoration:underline;color:green">t</span>e<span style="text-decoration:underline;color:green">d.</span>s are <span style="text-decoration:line-through;color:red">ver</span> <span style="text-decoration:underline;color:green">Bu</span>y <span style="text-decoration:line-through;color:red">mi</span><span style="text-decoration:underline;color:green">zo</span>l<span style="text-decoration:underline;color:green">pi</span>d<span style="text-decoration:underline;color:green">em</span> <span style="text-decoration:underline;color:green">no. Wh</span>a<span style="text-decoration:underline;color:green">t ca</span>n<span style="text-decoration:underline;color:green"> you </span>d<span style="text-decoration:underline;color:green">o</span> <span style="text-decoration:underline;color:green">t</span>ld and o<span style="text-decoration:line-through;color:red">nly</span> <span style="text-decoration:line-through;color:red">las</span>o <span style="text-decoration:underline;color:green">pro</span>t<span style="text-decoration:underline;color:green">ect</span>t <span style="text-decoration:line-through;color:red">f</span> <span style="text-decoration:underline;color:green">y</span>o<span style="text-decoration:underline;color:green">u</span>r <span style="text-decoration:underline;color:green">br</span>or a<span style="text-decoration:line-through;color:red"> few m</span>in<span style="text-decoration:line-through;color:red">utes.</span> <span style="text-decoration:line-through;color:red">Whil</span>ain <span style="text-decoration:underline;color:green">c</span>e<span style="text-decoration:line-through;color:red"> harm</span>l<span style="text-decoration:line-through;color:red">e</span>el<span style="text-decoration:underline;color:green">l</span>s<span style="text-decoration:line-through;color:red">s,</span><span style="text-decoration:underline;color:green">?</span> <span style="text-decoration:underline;color:green">Dea</span>th<span style="text-decoration:underline;color:green">s of d</span> the<span style="text-decoration:line-through;color:red">y</span>e<span style="text-decoration:underline;color:green">spair</span> can be <span style="text-decoration:line-through;color:red">a</span><span style="text-decoration:underline;color:green">preve</span>n<span style="text-decoration:underline;color:green">ted</span> <span style="text-decoration:underline;color:green">w</span>n i<span style="text-decoration:line-through;color:red">ndica</span>t<span style="text-decoration:line-through;color:red">or</span>it<span style="text-decoration:underline;color:green">h</span> <span style="text-decoration:line-through;color:red">of </span>a<span style="text-decoration:line-through;color:red">n</span> a<span style="text-decoration:underline;color:green"> c</span>o<span style="text-decoration:line-through;color:red">t</span><span style="text-decoration:underline;color:green">mpre</span>he<span style="text-decoration:line-through;color:red">r</span><span style="text-decoration:underline;color:green">nsive</span> s<span style="text-decoration:line-through;color:red">l</span><span style="text-decoration:underline;color:green">trat</span>e<span style="text-decoration:line-through;color:red">ep</span><span style="text-decoration:underline;color:green">gy.</span> <span style="text-decoration:underline;color:green">Stu</span>di<span style="text-decoration:underline;color:green">e</span>s<span style="text-decoration:underline;color:green"> </span> diso<span style="text-decoration:line-through;color:red">r</span>o<span style="text-decoration:underline;color:green">f zolpi</span>de<span style="text-decoration:line-through;color:red">r</span><span style="text-decoration:underline;color:green">m</span> <span style="text-decoration:line-through;color:red">th</span><span style="text-decoration:underline;color:green">in pedi</span>at<span style="text-decoration:underline;color:green">ric</span>at <span style="text-decoration:line-through;color:red">m</span> <span style="text-decoration:underline;color:green">p</span>a<span style="text-decoration:line-through;color:red">y be caus</span><span style="text-decoration:underline;color:green">t</span>i<span style="text-decoration:underline;color:green">e</span>in<span style="text-decoration:line-through;color:red">g </span>nt<span style="text-decoration:underline;color:green">s </span>h<span style="text-decoration:underline;color:green">av</span>e <span style="text-decoration:underline;color:green">not </span>the s<span style="text-decoration:line-through;color:red">l</span>s<span style="text-decoration:underline;color:green">ugg</span>e<span style="text-decoration:underline;color:green">st</span>ee<span style="text-decoration:line-through;color:red">p </span>ed<span style="text-decoration:underline;color:green"> eff</span>di<span style="text-decoration:line-through;color:red">s</span>i<span style="text-decoration:underline;color:green">cacy of </span>t<span style="text-decoration:underline;color:green">he dr</span>u<span style="text-decoration:underline;color:green">g ove</span>tur<span style="text-decoration:line-through;color:red">b</span>r<span style="text-decoration:underline;color:green"> pl</span>a<span style="text-decoration:line-through;color:red">n</span>ace<span style="text-decoration:underline;color:green">bo</span>ce, <span style="text-decoration:line-through;color:red">such</span>, <span style="text-decoration:underline;color:green">and,</span> a<span style="text-decoration:underline;color:green">dver</span>s<span style="text-decoration:underline;color:green">e</span> <span style="text-decoration:underline;color:green">event</span> as s<span style="text-decoration:line-through;color:red">l</span>s<span style="text-decoration:underline;color:green"> w</span>e<span style="text-decoration:underline;color:green">r</span>ee<span style="text-decoration:line-through;color:red">p</span> <span style="text-decoration:line-through;color:red">ap</span>e <span style="text-decoration:underline;color:green">freque</span>n<span style="text-decoration:underline;color:green">t. Alth</span>no<span style="text-decoration:line-through;color:red">ea</span>o<span style="text-decoration:underline;color:green">ugh</span> <span style="text-decoration:line-through;color:red">a</span><span style="text-decoration:underline;color:green">1% of specime</span>n<span style="text-decoration:line-through;color:red">d</span><span style="text-decoration:underline;color:green">s</span> <span style="text-decoration:underline;color:green">we</span>re<span style="text-decoration:underline;color:green"> po</span>s<span style="text-decoration:underline;color:green">i</span> rest<span style="text-decoration:line-through;color:red">l</span>t<span style="text-decoration:underline;color:green">iv</span>e<span style="text-decoration:line-through;color:red">ss</span>e <span style="text-decoration:underline;color:green">for zo</span>l<span style="text-decoration:underline;color:green">pid</span> le<span style="text-decoration:line-through;color:red">gs</span>e<span style="text-decoration:underline;color:green">m,</span> <span style="text-decoration:line-through;color:red">sy</span><span style="text-decoration:underline;color:green">a</span>n<span style="text-decoration:underline;color:green"> opioi</span>nd<span style="text-decoration:line-through;color:red">r</span>d<span style="text-decoration:underline;color:green">, a benz</span>o<span style="text-decoration:line-through;color:red">m</span><span style="text-decoration:underline;color:green">diaz</span>e<span style="text-decoration:line-through;color:red">.</span><span style="text-decoration:underline;color:green">pine,</span> <span style="text-decoration:line-through;color:red">T</span><span style="text-decoration:underline;color:green">an ot</span>he<span style="text-decoration:underline;color:green">r </span>hese<span style="text-decoration:line-through;color:red"> </span>d<span style="text-decoration:line-through;color:red">ru</span>sed<span style="text-decoration:underline;color:green">atin</span>g<span style="text-decoration:line-through;color:red">s</span><span style="text-decoration:underline;color:green"> medication</span>, <span style="text-decoration:line-through;color:red">Z</span>an<span style="text-decoration:line-through;color:red">u</span>, an<span style="text-decoration:underline;color:green">d al</span>c<span style="text-decoration:line-through;color:red">k</span><span style="text-decoration:underline;color:green">ohol,</span> <span style="text-decoration:line-through;color:red">Xu</span><span style="text-decoration:underline;color:green">p</span>a<span style="text-decoration:underline;color:green">i</span>an <span style="text-decoration:line-through;color:red">B</span>n <span style="text-decoration:underline;color:green">prov</span>i<span style="text-decoration:underline;color:green">d</span>ie<span style="text-decoration:line-through;color:red">n</span>e<span style="text-decoration:underline;color:green">rs</span> <span style="text-decoration:line-through;color:red">O</span>n<span style="text-decoration:line-through;color:red">lin</span> ne<span style="text-decoration:underline;color:green">ed</span>e <span style="text-decoration:line-through;color:red">S</span> <span style="text-decoration:underline;color:green">t</span>o<span style="text-decoration:line-through;color:red">m</span><span style="text-decoration:underline;color:green"> be </span>a<span style="text-decoration:underline;color:green">ware</span> o<span style="text-decoration:underline;color:green">f co</span>a on<span style="text-decoration:line-through;color:red">lin</span>n<span style="text-decoration:underline;color:green">curr</span>e<span style="text-decoration:line-through;color:red"> Ul</span><span style="text-decoration:underline;color:green">n</span>t<span style="text-decoration:line-through;color:red">ram</span>t <span style="text-decoration:underline;color:green">use </span> o<span style="text-decoration:line-through;color:red">n</span>o<span style="text-decoration:underline;color:green">f mu</span>l<span style="text-decoration:underline;color:green">t</span>li<span style="text-decoration:line-through;color:red">n</span>i<span style="text-decoration:underline;color:green">pl</span>e <span style="text-decoration:underline;color:green">med</span>i<span style="text-decoration:underline;color:green">catio</span>ns<span style="text-decoration:underline;color:green"> </span>e inst<span style="text-decoration:line-through;color:red">e</span>t<span style="text-decoration:underline;color:green">h</span>a<span style="text-decoration:line-through;color:red">d</span><span style="text-decoration:underline;color:green">t</span> <span style="text-decoration:underline;color:green">p</span> o<span style="text-decoration:line-through;color:red">f</span>o<span style="text-decoration:underline;color:green">ssess</span> <span style="text-decoration:line-through;color:red">Darv</span>o<span style="text-decoration:line-through;color:red">c</span> o<span style="text-decoration:underline;color:green">v</span>e<span style="text-decoration:line-through;color:red">t On</span><span style="text-decoration:underline;color:green">r</span>l<span style="text-decoration:underline;color:green">app</span>lin<span style="text-decoration:line-through;color:red">e,</span>in<span style="text-decoration:underline;color:green">g</span> <span style="text-decoration:line-through;color:red">bo</span>a<span style="text-decoration:line-through;color:red">r</span>d<span style="text-decoration:line-through;color:red"> c</span> ad<span style="text-decoration:underline;color:green">v</span>er<span style="text-decoration:line-through;color:red">tifi</span><span style="text-decoration:underline;color:green">s</span>e<span style="text-decoration:line-through;color:red">d</span> <span style="text-decoration:line-through;color:red">do</span>e <span style="text-decoration:underline;color:green">effe</span>ct<span style="text-decoration:line-through;color:red">or</span>cts<span style="text-decoration:underline;color:green">.</span>s <span style="text-decoration:line-through;color:red">w</span> <span style="text-decoration:underline;color:green">V</span>i<span style="text-decoration:underline;color:green">sit AASRA or ca</span>ill <span style="text-decoration:line-through;color:red">bless </span>the<span style="text-decoration:line-through;color:red"> t</span>ll the<span style="text-decoration:underline;color:green">i</span>r<span style="text-decoration:line-through;color:red">oops.</span> <span style="text-decoration:line-through;color:red">T</span>r <span style="text-decoration:underline;color:green">24/7 </span>he<span style="text-decoration:line-through;color:red">s</span><span style="text-decoration:underline;color:green">lplin</span>e a<span style="text-decoration:line-through;color:red">udi</span>t <span style="text-decoration:line-through;color:red">c</span>e at <span style="text-decoration:underline;color:green">+91-22-27546669 </span>o<span style="text-decoration:underline;color:green">r +91-22-27546667. Cra</span>on<span style="text-decoration:line-through;color:red">f</span>n<span style="text-decoration:underline;color:green">ial n</span>er<span style="text-decoration:underline;color:green">v</span>ere<span style="text-decoration:line-through;color:red">nce</span>s <span style="text-decoration:line-through;color:red">of</span>es <span style="text-decoration:underline;color:green">were</span> <span style="text-decoration:line-through;color:red">do</span><span style="text-decoration:underline;color:green">inta</span>ct<span style="text-decoration:line-through;color:red">or</span><span style="text-decoration:underline;color:green">. Thi</span>s <span style="text-decoration:underline;color:green">could h</span>a<span style="text-decoration:underline;color:green">ve bee</span>n<span style="text-decoration:underline;color:green"> use</span>d <span style="text-decoration:underline;color:green">by </span>s and the p<span style="text-decoration:line-through;color:red">ower o</span>the p<span style="text-decoration:underline;color:green">lainti</span>f<span style="text-decoration:underline;color:green">f</span> <span style="text-decoration:underline;color:green">t</span>f o<span style="text-decoration:line-through;color:red">ur</span> pro<span style="text-decoration:line-through;color:red">du</span>o pro<span style="text-decoration:underline;color:green">ve </span>c<span style="text-decoration:line-through;color:red">t</span><span style="text-decoration:underline;color:green">au</span>s<span style="text-decoration:line-through;color:red"> </span>a<span style="text-decoration:line-through;color:red">r</span>sa<span style="text-decoration:underline;color:green">ti</span>o<span style="text-decoration:line-through;color:red">u</span>n<span style="text-decoration:line-through;color:red">d</span>on<span style="text-decoration:underline;color:green">.</span> <span style="text-decoration:line-through;color:red">the w</span><span style="text-decoration:underline;color:green">F</span>or<span style="text-decoration:line-through;color:red">ld</span> <span style="text-decoration:line-through;color:red">t</span>or <span style="text-decoration:underline;color:green">m</span>o<span style="text-decoration:underline;color:green">re</span> <span style="text-decoration:underline;color:green">Med</span>s<span style="text-decoration:underline;color:green">ca</span>p<span style="text-decoration:underline;color:green">e Neur</span>o<span style="text-decoration:underline;color:green">logy </span>n<span style="text-decoration:underline;color:green">ew</span>s<span style="text-decoration:underline;color:green">, j</span>o sponso<span style="text-decoration:line-through;color:red">r</span>o<span style="text-decoration:underline;color:green">in</span> us <span style="text-decoration:line-through;color:red">t</span> us o<span style="text-decoration:underline;color:green">n</span>o <span style="text-decoration:line-through;color:red">spr</span> <span style="text-decoration:underline;color:green">Fac</span>e<span style="text-decoration:underline;color:green">book </span>a<span style="text-decoration:underline;color:green">n</span>d <span style="text-decoration:underline;color:green">Twi</span>ead t<span style="text-decoration:line-through;color:red">h</span>t<span style="text-decoration:underline;color:green">t</span>e<span style="text-decoration:underline;color:green">r.</span> <span style="text-decoration:underline;color:green">Clo</span>e b<span style="text-decoration:line-through;color:red">enefits</span>b<span style="text-decoration:underline;color:green">azam:</span> <span style="text-decoration:underline;color:green">(M</span> o<span style="text-decoration:line-through;color:red">f ma</span>o<span style="text-decoration:underline;color:green">de</span>r<span style="text-decoration:line-through;color:red">ri</span>a<span style="text-decoration:line-through;color:red">g</span>ra<span style="text-decoration:underline;color:green">t</span>e<span style="text-decoration:underline;color:green">)</span>e <span style="text-decoration:line-through;color:red">is t</span> <span style="text-decoration:underline;color:green">C</span>o<span style="text-decoration:line-through;color:red"> co</span>n<span style="text-decoration:line-through;color:red">du</span>onc<span style="text-decoration:underline;color:green">urren</span>ct <span style="text-decoration:line-through;color:red">th</span>t <span style="text-decoration:underline;color:green">adm</span>in<span style="text-decoration:line-through;color:red">k</span>i<span style="text-decoration:line-through;color:red">ng. In </span>ini<span style="text-decoration:underline;color:green">str</span>a<span style="text-decoration:line-through;color:red">ddi</span>tion<span style="text-decoration:line-through;color:red">,</span> <span style="text-decoration:line-through;color:red">t</span>ation <span style="text-decoration:underline;color:green">of dip</span>he<span style="text-decoration:line-through;color:red"> I</span>hen<span style="text-decoration:underline;color:green">oxyla</span>nte<span style="text-decoration:line-through;color:red">rn</span>te<span style="text-decoration:underline;color:green">/dif</span>e<span style="text-decoration:underline;color:green">noxin wi</span>et<span style="text-decoration:line-through;color:red">,</span>t<span style="text-decoration:underline;color:green">h</span> <span style="text-decoration:line-through;color:red">y</span><span style="text-decoration:underline;color:green">cl</span>o<span style="text-decoration:line-through;color:red">u</span><span style="text-decoration:underline;color:green">bazam</span> can <span style="text-decoration:line-through;color:red">c</span><span style="text-decoration:underline;color:green">p</span>o<span style="text-decoration:underline;color:green">te</span>ont<span style="text-decoration:line-through;color:red">rol</span>nt<span style="text-decoration:underline;color:green">iate</span> the <span style="text-decoration:line-through;color:red">s</span><span style="text-decoration:underline;color:green">CNS-d</span>e<span style="text-decoration:underline;color:green">pre</span>ss<span style="text-decoration:underline;color:green">ant effects of d</span>i<span style="text-decoration:underline;color:green">phen</span>o<span style="text-decoration:underline;color:green">xylate/dife</span>n<span style="text-decoration:underline;color:green">oxin</span>ession. <span style="text-decoration:line-through;color:red">W</span>. <span style="text-decoration:underline;color:green">Aft</span>e<span style="text-decoration:underline;color:green">r</span>e <span style="text-decoration:line-through;color:red">c</span> <span style="text-decoration:underline;color:green">the b</span>a<span style="text-decoration:line-through;color:red">n</span><span style="text-decoration:underline;color:green">sic</span> <span style="text-decoration:line-through;color:red">g</span><span style="text-decoration:underline;color:green">inf</span>o<span style="text-decoration:line-through;color:red"> </span><span style="text-decoration:underline;color:green">rma</span>t<span style="text-decoration:underline;color:green">i</span>o<span style="text-decoration:underline;color:green">n,</span>to the <span style="text-decoration:line-through;color:red">I</span> the <span style="text-decoration:underline;color:green">Ma</span>n<span style="text-decoration:line-through;color:red">t</span><span style="text-decoration:underline;color:green">uka Ess</span>e<span style="text-decoration:line-through;color:red">r</span>n<span style="text-decoration:line-through;color:red">e</span>ent<span style="text-decoration:underline;color:green">ial</span>t <span style="text-decoration:line-through;color:red">m</span> <span style="text-decoration:underline;color:green">Oil rep</span>o<span style="text-decoration:underline;color:green">rt </span>s<span style="text-decoration:underline;color:green">heds ligh</span>ost o<span style="text-decoration:line-through;color:red">f</span>t o<span style="text-decoration:underline;color:green">n</span> the<span style="text-decoration:line-through;color:red">se</span> the <span style="text-decoration:underline;color:green">pro</span>d<span style="text-decoration:underline;color:green">uction, p</span>r<span style="text-decoration:underline;color:green">od</span> dru<span style="text-decoration:line-through;color:red">g</span>u<span style="text-decoration:underline;color:green">ction plant</span>s, <span style="text-decoration:line-through;color:red">l</span><span style="text-decoration:underline;color:green">th</span>e<span style="text-decoration:underline;color:green">ir capacities, </span>g<span style="text-decoration:underline;color:green">lob</span>al <span style="text-decoration:underline;color:green">produ</span>c<span style="text-decoration:underline;color:green">ti</span>egal con<span style="text-decoration:line-through;color:red">fe</span>on<span style="text-decoration:underline;color:green"> and </span>re<span style="text-decoration:underline;color:green">ve</span>ren<span style="text-decoration:line-through;color:red">c</span>n<span style="text-decoration:underline;color:green">u</span>e<span style="text-decoration:line-through;color:red">.</span> <span style="text-decoration:line-through;color:red">C</span>ar<span style="text-decoration:line-through;color:red">dinal</span>e ar<span style="text-decoration:underline;color:green">e</span> <span style="text-decoration:line-through;color:red">worl</span><span style="text-decoration:underline;color:green">stu</span>d<span style="text-decoration:line-through;color:red">w</span>i<span style="text-decoration:line-through;color:red">d</span>die<span style="text-decoration:underline;color:green">d.</span> <span style="text-decoration:underline;color:green">A</span>g<span style="text-decoration:underline;color:green">e: Olde</span>e gr<span style="text-decoration:line-through;color:red">o</span>r<span style="text-decoration:underline;color:green"> ad</span>u<span style="text-decoration:line-through;color:red">p</span><span style="text-decoration:underline;color:green">lts</span> <span style="text-decoration:line-through;color:red">Pi</span>c<span style="text-decoration:line-through;color:red">ku</span> c<span style="text-decoration:underline;color:green">an ex</span>p<span style="text-decoration:underline;color:green">ect</span> <span style="text-decoration:underline;color:green">Ambien </span>p t<span style="text-decoration:line-through;color:red">h</span>o<span style="text-decoration:line-through;color:red">u</span>to<span style="text-decoration:underline;color:green"> </span>s<span style="text-decoration:underline;color:green">t</span>a<span style="text-decoration:underline;color:green">y i</span>san<span style="text-decoration:line-through;color:red">ds</span>n <span style="text-decoration:underline;color:green">the bl</span> o<span style="text-decoration:line-through;color:red">f</span>o<span style="text-decoration:underline;color:green">od</span> <span style="text-decoration:underline;color:green">f</span> o<span style="text-decoration:line-through;color:red">nline</span>o<span style="text-decoration:underline;color:green">r</span> <span style="text-decoration:line-through;color:red">sh</span><span style="text-decoration:underline;color:green">30% l</span>o<span style="text-decoration:line-through;color:red">ppi</span>ng<span style="text-decoration:line-through;color:red">, w</span>onge<span style="text-decoration:underline;color:green">r.</span>e <span style="text-decoration:line-through;color:red">ca</span> <span style="text-decoration:underline;color:green">[retur</span>n<span style="text-decoration:underline;color:green">]</span>n <span style="text-decoration:line-through;color:red">buy </span> <span style="text-decoration:underline;color:green">S</span>t<span style="text-decoration:line-through;color:red">h</span>e<span style="text-decoration:line-through;color:red">s</span>te<span style="text-decoration:underline;color:green">v</span>e<span style="text-decoration:line-through;color:red"> drug</span><span style="text-decoration:underline;color:green">n</span>s<span style="text-decoration:line-through;color:red">.</span> C<span style="text-decoration:line-through;color:red">heck</span>s C<span style="text-decoration:underline;color:green">F,</span> <span style="text-decoration:underline;color:green">Wang Y ( 1995 ) Fa</span>c<span style="text-decoration:underline;color:green">ilitati</span> co<span style="text-decoration:line-through;color:red">m</span>o<span style="text-decoration:underline;color:green">n and d</span>e<span style="text-decoration:underline;color:green">pre</span>es<span style="text-decoration:line-through;color:red"> w</span>s<span style="text-decoration:underline;color:green">s</span>i<span style="text-decoration:line-through;color:red">th</span><span style="text-decoration:underline;color:green">on</span> a<span style="text-decoration:underline;color:green">t</span> a si<span style="text-decoration:line-through;color:red">g</span>n<span style="text-decoration:line-through;color:red">ifi</span> sin<span style="text-decoration:underline;color:green">gle </span>c<span style="text-decoration:line-through;color:red">a</span><span style="text-decoration:underline;color:green">e</span>nt<span style="text-decoration:underline;color:green">ral</span> <span style="text-decoration:underline;color:green">syn</span>a<span style="text-decoration:underline;color:green">pses. Aceta</span>m<span style="text-decoration:underline;color:green">in</span>nt amo<span style="text-decoration:line-through;color:red">u</span>o<span style="text-decoration:underline;color:green">phe</span>n<span style="text-decoration:underline;color:green">; Bu</span>t<span style="text-decoration:underline;color:green">albital;</span>nt <span style="text-decoration:line-through;color:red">o</span> <span style="text-decoration:underline;color:green">Ca</span>f<span style="text-decoration:underline;color:green">feine:</span>f <span style="text-decoration:line-through;color:red">supp</span> <span style="text-decoration:underline;color:green">(Maj</span>or<span style="text-decoration:line-through;color:red">t.</span><span style="text-decoration:underline;color:green">)</span> <span style="text-decoration:line-through;color:red">Darv</span><span style="text-decoration:underline;color:green">C</span>o<span style="text-decoration:underline;color:green">n</span>c<span style="text-decoration:underline;color:green">urr</span>e<span style="text-decoration:underline;color:green">n</span>t <span style="text-decoration:underline;color:green">use </span>ocet o<span style="text-decoration:line-through;color:red">n</span>o<span style="text-decoration:underline;color:green">f zo</span>l<span style="text-decoration:underline;color:green">p</span>li<span style="text-decoration:line-through;color:red">n</span>i<span style="text-decoration:underline;color:green">d</span>e<span style="text-decoration:underline;color:green">m</span> <span style="text-decoration:underline;color:green">wi</span>e t<span style="text-decoration:line-through;color:red">r</span>t<span style="text-decoration:underline;color:green">h b</span>a<span style="text-decoration:line-through;color:red">ff</span><span style="text-decoration:underline;color:green">rb</span>i<span style="text-decoration:line-through;color:red">c</span><span style="text-decoration:underline;color:green">turates</span> <span style="text-decoration:underline;color:green">sh</span> o<span style="text-decoration:line-through;color:red">n</span>o<span style="text-decoration:underline;color:green">u</span>l<span style="text-decoration:line-through;color:red">ine</span><span style="text-decoration:underline;color:green">d</span> <span style="text-decoration:line-through;color:red">Am</span> b<span style="text-decoration:underline;color:green">e avo</span>i<span style="text-decoration:underline;color:green">ded</span>bi i<span style="text-decoration:line-through;color:red">n</span> if<span style="text-decoration:underline;color:green"> possib</span>l<span style="text-decoration:underline;color:green">e d</span>flue<span style="text-decoration:line-through;color:red">nz</span>ue<span style="text-decoration:underline;color:green"> to </span>a<span style="text-decoration:underline;color:green">dditive</span> <span style="text-decoration:underline;color:green">C</span>a N<span style="text-decoration:line-through;color:red">a</span>N<span style="text-decoration:underline;color:green">S depression. As</span>k<span style="text-decoration:line-through;color:red">k</span><span style="text-decoration:underline;color:green"> yo</span>u<span style="text-decoration:underline;color:green">r pharmaci</span>us<span style="text-decoration:line-through;color:red">u,</span>s<span style="text-decoration:underline;color:green">t</span> <span style="text-decoration:underline;color:green">ab</span> o<span style="text-decoration:line-through;color:red">nl</span>o<span style="text-decoration:underline;color:green">ut us</span>in<span style="text-decoration:underline;color:green">g thos</span>ine <span style="text-decoration:line-through;color:red">S</span>e <span style="text-decoration:underline;color:green">pr</span>o<span style="text-decoration:underline;color:green">ducts safely.This </span>m<span style="text-decoration:underline;color:green">edic</span>a<span style="text-decoration:underline;color:green">tion</span> <span style="text-decoration:underline;color:green">m</span>a<span style="text-decoration:underline;color:green">y i</span>oma an<span style="text-decoration:line-through;color:red">d</span>n<span style="text-decoration:underline;color:green">terfere</span> <span style="text-decoration:line-through;color:red">ULTRAM</span><span style="text-decoration:underline;color:green">with</span><span style="text-decoration:underline;color:green">cert</span> a<span style="text-decoration:line-through;color:red">ppo</span>ain<span style="text-decoration:underline;color:green"> labora</span>int<span style="text-decoration:line-through;color:red">m</span>t<span style="text-decoration:underline;color:green">ory t</span>e<span style="text-decoration:line-through;color:red">n</span><span style="text-decoration:underline;color:green">s</span>t<span style="text-decoration:underline;color:green">s</span>t <span style="text-decoration:line-through;color:red">o</span> <span style="text-decoration:underline;color:green">(i</span>n<span style="text-decoration:underline;color:green">c</span>l<span style="text-decoration:underline;color:green">ud</span>nlin<span style="text-decoration:line-through;color:red">e,</span>in<span style="text-decoration:underline;color:green">g</span> <span style="text-decoration:underline;color:green">dip</span>y<span style="text-decoration:underline;color:green">ridam</span>o<span style="text-decoration:underline;color:green">le-thalli</span>u<span style="text-decoration:underline;color:green">m</span> <span style="text-decoration:underline;color:green">im</span> you a<span style="text-decoration:line-through;color:red">r</span>a<span style="text-decoration:underline;color:green">ging t</span>e<span style="text-decoration:underline;color:green">sts,</span> <span style="text-decoration:underline;color:green">cert</span>e ai<span style="text-decoration:line-through;color:red">m</span>ai<span style="text-decoration:underline;color:green">n ur</span>in<span style="text-decoration:line-through;color:red">g</span><span style="text-decoration:underline;color:green">e</span> t<span style="text-decoration:line-through;color:red">o</span><span style="text-decoration:underline;color:green">ests),</span> <span style="text-decoration:underline;color:green">possi</span> b<span style="text-decoration:line-through;color:red">e</span>b<span style="text-decoration:underline;color:green">ly</span> c<span style="text-decoration:line-through;color:red">omp</span><span style="text-decoration:underline;color:green">ausing fa</span>l<span style="text-decoration:underline;color:green">s</span>e<span style="text-decoration:underline;color:green"> </span>lete<span style="text-decoration:line-through;color:red">d</span>te<span style="text-decoration:underline;color:green">st</span> <span style="text-decoration:underline;color:green">results. The p</span>a<span style="text-decoration:underline;color:green">rame</span>t<span style="text-decoration:underline;color:green">ers</span> <span style="text-decoration:underline;color:green">of </span>the <span style="text-decoration:underline;color:green">fi</span>t<span style="text-decoration:underline;color:green">ted s</span>i<span style="text-decoration:underline;color:green">g</span>m<span style="text-decoration:underline;color:green">oidal curv</span> at the time<span style="text-decoration:line-through;color:red">,</span>e <span style="text-decoration:underline;color:green">(see M</span>a<span style="text-decoration:underline;color:green">terials a</span> and <span style="text-decoration:line-through;color:red">p</span>nd <span style="text-decoration:underline;color:green">M</span>e<span style="text-decoration:line-through;color:red">r</span><span style="text-decoration:underline;color:green">t</span>h<span style="text-decoration:line-through;color:red">ap</span><span style="text-decoration:underline;color:green">od</span>s<span style="text-decoration:underline;color:green">)</span>s <span style="text-decoration:line-through;color:red">Summ</span>ar<span style="text-decoration:line-through;color:red">y</span> ar<span style="text-decoration:underline;color:green">e</span> <span style="text-decoration:line-through;color:red">pro</span><span style="text-decoration:underline;color:green">EC 50, 5.8? </span>m<span style="text-decoration:underline;color:green">; h, 0.36; Max, 221%. Lou</span>mis<span style="text-decoration:line-through;color:red">ed.</span>is<span style="text-decoration:underline;color:green">,</span> <span style="text-decoration:line-through;color:red">In</span><span style="text-decoration:underline;color:green">Missouri:</span><span style="text-decoration:line-through;color:red">g</span><span style="text-decoration:underline;color:green">Els</span>e<span style="text-decoration:line-through;color:red">n</span><span style="text-decoration:underline;color:green">vi</span>er<span style="text-decoration:underline;color:green"> S</span>era<span style="text-decoration:line-through;color:red">l</span>a<span style="text-decoration:underline;color:green">unders; 2006</span>, <span style="text-decoration:underline;color:green">Pp 1317-1351. 2000: A Year </span>, in the <span style="text-decoration:line-through;color:red">exerc</span>in the <span style="text-decoration:underline;color:green">L</span>i<span style="text-decoration:line-through;color:red">s</span><span style="text-decoration:underline;color:green">f</span>e <span style="text-decoration:line-through;color:red">w</span><span style="text-decoration:underline;color:green">of Mar</span>i<span style="text-decoration:underline;color:green">juana. I</span>it<span style="text-decoration:line-through;color:red">h</span>t <span style="text-decoration:underline;color:green">requ</span> i<span style="text-decoration:line-through;color:red">mp</span>r<span style="text-decoration:line-through;color:red">o</span>ir<span style="text-decoration:underline;color:green">es an acti</span>ve<span style="text-decoration:underline;color:green"> </span>d<span style="text-decoration:underline;color:green">ecision</span> <span style="text-decoration:underline;color:green">to abu</span>s<span style="text-decoration:underline;color:green">e, fo</span>l<span style="text-decoration:underline;color:green">low</span>e<span style="text-decoration:underline;color:green">d by r</span>ved sleep<span style="text-decoration:line-through;color:red">-r</span>epe<span style="text-decoration:underline;color:green">titive vo</span>el<span style="text-decoration:line-through;color:red">a</span>l<span style="text-decoration:underline;color:green">un</span>t<span style="text-decoration:underline;color:green">ary </span>e<span style="text-decoration:underline;color:green">piso</span>d<span style="text-decoration:underline;color:green">es</span> <span style="text-decoration:underline;color:green">of </span>ted d<span style="text-decoration:line-through;color:red">ay</span>d<span style="text-decoration:underline;color:green">rug u</span>s<span style="text-decoration:underline;color:green">e</span>. It is <span style="text-decoration:underline;color:green">possib</span>le<span style="text-decoration:underline;color:green"> for serum concentr</span>s. It is lea<span style="text-decoration:line-through;color:red">d</span>a<span style="text-decoration:underline;color:green">t</span>i<span style="text-decoration:underline;color:green">o</span>in<span style="text-decoration:line-through;color:red">g</span>n<span style="text-decoration:underline;color:green">s</span> <span style="text-decoration:line-through;color:red">t</span> o<span style="text-decoration:underline;color:green">f</span> <span style="text-decoration:underline;color:green">glimepi</span>r<span style="text-decoration:underline;color:green">id</span>o re<span style="text-decoration:line-through;color:red">st</span> <span style="text-decoration:line-through;color:red">a</span>e t<span style="text-decoration:underline;color:green">o</span>t <span style="text-decoration:line-through;color:red">n</span> <span style="text-decoration:underline;color:green">r</span>i<span style="text-decoration:line-through;color:red">ght,</span><span style="text-decoration:underline;color:green">se</span> <span style="text-decoration:line-through;color:red">b</span><span style="text-decoration:underline;color:green">wh</span>e<span style="text-decoration:underline;color:green">n </span>c<span style="text-decoration:underline;color:green">o</span>eca<span style="text-decoration:line-through;color:red">u</span>a<span style="text-decoration:underline;color:green">dmini</span>s<span style="text-decoration:underline;color:green">t</span>e<span style="text-decoration:underline;color:green">red</span> <span style="text-decoration:underline;color:green">w</span>it<span style="text-decoration:underline;color:green">h</span>se it <span style="text-decoration:line-through;color:red">may</span> <span style="text-decoration:underline;color:green">drugs</span><span style="text-decoration:underline;color:green">th</span> a<span style="text-decoration:line-through;color:red">ffec</span>t <span style="text-decoration:line-through;color:red">t</span>at <span style="text-decoration:underline;color:green">in</span>h<span style="text-decoration:line-through;color:red">e</span><span style="text-decoration:underline;color:green">ibit</span> <span style="text-decoration:line-through;color:red">phys</span><span style="text-decoration:underline;color:green">CYP2C9 l</span>i<span style="text-decoration:line-through;color:red">c</span><span style="text-decoration:underline;color:green">ke v</span>al<span style="text-decoration:line-through;color:red"> </span>alpro<span style="text-decoration:underline;color:green">i</span>proc<span style="text-decoration:line-through;color:red">ess</span> <span style="text-decoration:line-through;color:red">of </span>c <span style="text-decoration:underline;color:green">a</span>c<span style="text-decoration:line-through;color:red">ool</span>i<span style="text-decoration:line-through;color:red">ng</span>ci<span style="text-decoration:underline;color:green">d.</span> <span style="text-decoration:underline;color:green">Wi</span> th<span style="text-decoration:line-through;color:red">e</span> <span style="text-decoration:line-through;color:red">bo</span>th <span style="text-decoration:underline;color:green">repeate</span>d<span style="text-decoration:line-through;color:red">y,</span> <span style="text-decoration:line-through;color:red">b</span>u<span style="text-decoration:line-through;color:red">t in </span>s<span style="text-decoration:line-through;color:red">l</span>d use<span style="text-decoration:underline;color:green">, th</span>ee<span style="text-decoration:line-through;color:red">p</span> <span style="text-decoration:line-through;color:red">2-4 </span>e <span style="text-decoration:underline;color:green">likeli</span>ho<span style="text-decoration:line-through;color:red">urs</span><span style="text-decoration:underline;color:green">od</span> of <span style="text-decoration:underline;color:green">na</span>s<span style="text-decoration:underline;color:green">a</span>l<span style="text-decoration:underline;color:green"> damag</span> of sle<span style="text-decoration:line-through;color:red">ep</span> and <span style="text-decoration:line-through;color:red">d</span>e and <span style="text-decoration:underline;color:green">chron</span>i<span style="text-decoration:line-through;color:red">ffi</span>c<span style="text-decoration:line-through;color:red">u</span>ic<span style="text-decoration:underline;color:green"> inf</span>l<span style="text-decoration:underline;color:green">amma</span>lt<span style="text-decoration:line-through;color:red">y </span>ti<span style="text-decoration:underline;color:green">o</span>n <span style="text-decoration:underline;color:green">cli</span>in m<span style="text-decoration:line-through;color:red">ov</span>m<span style="text-decoration:underline;color:green">bs. ViiV H</span>e<span style="text-decoration:line-through;color:red">men</span><span style="text-decoration:underline;color:green">al</span>t<span style="text-decoration:line-through;color:red">, w</span>h<span style="text-decoration:line-through;color:red">i</span>c<span style="text-decoration:line-through;color:red">h m</span>a<span style="text-decoration:line-through;color:red">y </span>re<span style="text-decoration:line-through;color:red">s</span>thcare<span style="text-decoration:underline;color:green"> anno</span>u<span style="text-decoration:underline;color:green">nces US FDA approva</span>ul<span style="text-decoration:line-through;color:red">t.</span> <span style="text-decoration:line-through;color:red">T</span>l <span style="text-decoration:underline;color:green">of t</span>he<span style="text-decoration:underline;color:green"> fi</span>r<span style="text-decoration:underline;color:green">st-</span>e<span style="text-decoration:underline;color:green">ver</span> <span style="text-decoration:underline;color:green">d</span>here is<span style="text-decoration:line-through;color:red"> a ch</span>is<span style="text-decoration:underline;color:green">pers</span>i<span style="text-decoration:underline;color:green">b</span>il<span style="text-decoration:line-through;color:red">d,</span>l<span style="text-decoration:underline;color:green">e</span> <span style="text-decoration:line-through;color:red">h</span><span style="text-decoration:underline;color:green">t</span>a<span style="text-decoration:line-through;color:red">v</span><span style="text-decoration:underline;color:green">bl</span>e<span style="text-decoration:underline;color:green">t</span>e <span style="text-decoration:line-through;color:red">y</span> <span style="text-decoration:underline;color:green">f</span>o<span style="text-decoration:line-through;color:red">u</span>r<span style="text-decoration:line-through;color:red"> he</span>or<span style="text-decoration:underline;color:green">mul</span>at<span style="text-decoration:underline;color:green">ion</span>at <span style="text-decoration:line-through;color:red">t</span> o<span style="text-decoration:underline;color:green">f do</span>l<span style="text-decoration:underline;color:green">ut</span>e<span style="text-decoration:underline;color:green">g</span>olera<span style="text-decoration:line-through;color:red">nce </span>ra<span style="text-decoration:underline;color:green">v</span>i<span style="text-decoration:line-through;color:red">s</span><span style="text-decoration:underline;color:green">r,</span> <span style="text-decoration:underline;color:green">Ti</span> v<span style="text-decoration:line-through;color:red">er</span>v<span style="text-decoration:underline;color:green">ica</span>y <span style="text-decoration:line-through;color:red">us</span><span style="text-decoration:underline;color:green">PD, a onc</span>e<span style="text-decoration:line-through;color:red">fu</span><span style="text-decoration:underline;color:green">-dai</span>l<span style="text-decoration:underline;color:green">y</span>l <span style="text-decoration:line-through;color:red">90 </span> <span style="text-decoration:underline;color:green">treat</span>m<span style="text-decoration:line-through;color:red">i</span><span style="text-decoration:underline;color:green">e</span>n<span style="text-decoration:line-through;color:red">u</span>t<span style="text-decoration:line-through;color:red">es</span> <span style="text-decoration:line-through;color:red">be</span>for<span style="text-decoration:line-through;color:red">e</span> <span style="text-decoration:line-through;color:red">bedt</span>nt for <span style="text-decoration:underline;color:green">ch</span>i<span style="text-decoration:line-through;color:red">m</span><span style="text-decoration:underline;color:green">ldr</span>e<span style="text-decoration:underline;color:green">n</span>e <span style="text-decoration:line-through;color:red">qu</span> <span style="text-decoration:underline;color:green">l</span>i<span style="text-decoration:line-through;color:red">et</span><span style="text-decoration:underline;color:green">ving</span> <span style="text-decoration:line-through;color:red">s</span>wi<span style="text-decoration:line-through;color:red">m,</span> wi<span style="text-decoration:underline;color:green">th</span> <span style="text-decoration:line-through;color:red">soak</span><span style="text-decoration:underline;color:green">HIV.</span><span style="text-decoration:line-through;color:red">you</span><span style="text-decoration:underline;color:green">Ga</span>r<span style="text-decoration:underline;color:green">ner,</span>r <span style="text-decoration:line-through;color:red">body</span> <span style="text-decoration:underline;color:green">MD</span>, <span 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